Page 7 - Dosage 1-part2 -ebook

30/10/2025, 00:02 Pharmaceutical Solutions & Sterile Dosage Forms

Liquid dosage forms (LDFs)

Liquid dosage forms are dosage forms (pharmaceutical formulations that contain one or
more APIs and excipients in a liquid state.

These might be: External use

Solution (Aqueous or Non-aqueous)
Suspension
Emulsion (W/O or O/W)

Intended for:

Internal use

Advantages and disadvantages of LDFs

Advantages Disadvantages
The oldest pharmaceutical formulations
Many drugs are inherently unstable, and
instability is increased when a drug is
present in solution.

Rapid drug action, allowing their use in emergencies. Many drugs are poorly soluble in water.

Liquids are bulky and less easy for the
patient to carry compared to solid dosage
forms.

Oral solutions are easily swallowed and are beneficial Liquids are also more expensive to
for patients for whom swallowing may be difficult, e.g. transport, which increases the medicine's
Children and older people. cost.

Solutions are easier to manufacture compared to The packaging of pharmaceutical
other dosage forms. solutions requires materials of higher
quality.

file:///C:/Users/sara talaat/Downloads/solutions and sterile sols.HTML 4/77