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30/10/2025, 00:02 Pharmaceutical Solutions & Sterile Dosage Forms

Introduction to Pharmaceutical solutions

Dispersed systems

systems consist of one component, the disperse phase distributed throughout another
component, the dispersion medium/ continuous phase.

Based on the size of dispersed phase, three types of dispersed systems are considered;

Colloid

Particle size (1nm- 500nm)
Visible under electron microscope
Cannot traverse semi permeable membrane and ultra filtration sets

Example: Hydrocolloids (Gels), nanoparticles (nanosuspension, nanoemulsion

True solution

is a mixture of two or more components that form a homogenous molecular dispersion
(Monophasic liquid dosage forms).

The components are referred to the solute & the solvent.
Solute: is the dissolved agent (usually the smaller portion).
Solvent: is the component in which the solute is dissolved (usually the greater portion).

In case of Pharmaceutical solution:

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