Page 156 - Pharmaceutics IV (02-06-01305)
P. 156

This case a five-fold difference.

BP test using Diphtheria & Tetanus toxoid involves

measurement of the antibody titres of the sera of the

inoculated animals.Similar test for assay of the potency of

killed poliomyelitis in chickens.

The potency of live vaccines cannot be assayed by dose-

response curve methods ,it may be estimated by counts of

viable particles.

Vaccines used in prophylaxis

1-Bacterial vaccines

Classification:

Disease               Type of vaccine

                      Killed organism

Cholera               Killed organism

Diphtheria                  Toxoid

Leprosy               Living organism (BCG)

Plague                Living attenuated or killed organism

Tetanus               Toxoid

Tuberculosis          Living organism (BCG)

Typhoid               Killed organism

Whooping cough Killed organism

                      -11-
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