Page 57 - Pharmaceutics IV (02-06-01305)
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Parenterals: Excipients & additives
• The use of excipients should not adversely affect the action of
the drug substance or cause any side effects or toxicity at the
concentrations used in a given formulation.
• Parenteral preparations may require the use of excipients that
should be biocompatible, be selected for the appropriate use
and to be included at the minimum efficient concentration
107
Parenterals: Excipients & additives
Vehicles & solvents
Water Nonaqueous vehicles
Water-miscible solvents
Oleaginous solvents
(water-immiscible)
108 54
Salma E. EL-Habashy
