Page 62 - controlled drug delievery

Intrauterine Modified release D.S.

Intrauterine delivery systems (IUD)

• Small T-shaped plastic device Polyethylene
that is inserted into the uterus
for sustained intrauterine drug Ethylene vinyl
delivery. acetate (EVA)
copolymer
• For contraception or hormonal
replacement therapy 38 mg progestrone
microcrystals &
• E.g.1 Progestasert® IUD BaSO4 suspended
in silicone oil
(65 µg progesterone/day for 1
year contraception)
• E.g.2 Mirena® IUD

(20 µg levonorgestrel/day for 5
years contraception)