Page 163 - Pharm.Org.Chem I 05-PC101 (1)

Electrophiles in benzene reactions

Reaction name E+ Product
Nitration Nitro benzene
SO3
Sulphonation Br+, Cl+ Benzensulphonic acid
Halogenation
Friedel-Crafts alkylation R+ Bromobenzene
chlorobenzene
alkylbenzene

Friedel-Crafts acylation Ketone

2025-026 Dr. Marwa El-Wakil 23

Nitration

Sulphonation

Halogenation

2025-026 Dr. Marwa El-Wakil 24

161