Page 167 - Pharm.Org.Chem I 05-PC101 (1)
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Friedel-Crafts Alkylation

  Step 1: Formation of an alkyl cation as an ion pair.

          Step 2: Attack of the alkyl carbocation.

          Step 3: Proton transfer regenerates the aromatic ring.

2025-026  Dr. Marwa El-Wakil                                      31

Note: whenever there is a possibility to rearrangement to a
more stable carbocation, then perform before electrophilic
substitution reaction on benzene.

2025-026  Dr. Marwa El-Wakil                                      32

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