Page 164 - Pharm.Org.Chem I 05-PC101 (1)
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Nitration

• Overall reaction:

• Mechanism:
• Step 1: generation of the electrophile

• Step 2:                                   nitrobenzene

         2025-026       Dr. Marwa El-Wakil                25

                 Sulphonation

• Overall reaction:

• Mechanism:            Dr. Marwa El-Wakil  Benzenesulphonic acid
                                                                                    26
           Note:
    Sulfur trioxide is
    the electrophile.

  2025-026

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