Page 112 - Pharmd general phytochemistry I-Final2024_LEUCTERS

Occurrence:
(1) Synthetically.

(2) By extraction from plant materials e.g. citrus fruits, tomatoes, potatoes.
Uses:
1- Vitamin C is essential for the normal functioning of living cells and is involved in

many enzyme reactions.
2- It is required for the development of cartilage, teeth and bones, wound healing and

for aiding the absorption of iron from the intestine.
3- The reducing and associated antioxidant properties of vitamin C are utilized in the

food industry and in the formulation of some pharmaceuticals.

Some Synthetic Glucose Derivatives

 In contrast to the above classes, there are a relatively small number of synthetic
carbohydrate drugs.

 Aurothioglucose and a Auranofin are two examples of gold derivatives of glucose.

1- Aurothioglucose

 It is known chemically as 1-β- D-glucosylthio gold.
Uses: Treatment of rheumatic arthritis (I.M.).

2- Auranofin

It is an alkyl phosphine gold coordination complex with peracetylated thioglucose.
Uses:
 Treatment of rheumatic arthritis; dose 3.0 mg orally, twice daily.

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