Page 74 - MNU-PM502- Pharmaeutical Microbiology Theoritical Book

Pharm D- Clinical Pharmacy Program Third Level Pharmaceutical Microbiology& Antimicrobials (PM 502)

Class 4 : Two or more critical Pouches
Multi-Variable variables.
Change color only when
exposed to a given
temperature for a
specified time

Class 5 : react to all the critical Integrators
Integrating variables of the specific
(Integrators) sterilization process
in steam cycles (time,
temperature, and
moisture)

Class 6 : All critical variables for Cycle Verification
Emulating specified sterilization They should only be used in the
indicator cycles specific cycle for which they are
(Cycle labeled
Verification)

3- Biological indicators
• Standardized bacterial spore preparations which are usually in the form either of
➢ suspensions in water or culture medium
➢ spores dried on paper, aluminum or plastic carriers

Self-contained biological indicator

Spore strip and nutrient medium are present in the same device ready for mixing

after use

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