Page 41 - New Employee Glossary

Glossary 41

Reporting application that maps directly to the General Ledger. Used during close
consolidation process and external reporting.

Market Capitalization (MCAP)

The market value of a firm’s common stock. It is obtained by multiplying the number of
shares outstanding by their current price per share. Generally, the U.S. market recognizes
three market cap divisions: large cap, midcap, and small cap, although the cutoffs between
the categories are not precise or fixed.

Marketing Authorization Application (MAA)

The vehicle through which drug sponsors formally propose that a regulatory agency approve
a new pharmaceutical for sale and marketing in Europe. European equivalent of a New Drug
Application (NDA)

Master Services Agreement (MSA)

Initial agreement signed by a vendor and Biogen to define the official terms of the
relationship, which is a legally binding document. The legal department has an official
template to be used.

Material Information

Information is material if "there is a substantial likelihood that a reasonable shareholder
would consider it important" in making an investment decision. Information is nonpublic if it
has not been disseminated in a manner making it available to investors generally.

Maximum Treatment Dose (MTD)

Highest dose of a treatment administered without unacceptable adverse events or toxicity

Mechanism of Action (MOA)

The specific biochemical interaction through which a drug substance produces its
pharmacological effect.

Medical Coder (MC)

Ad hoc SMT representative from Data Management that is responsible for coding the AEs,
Conmeds and other data as required.

Medical Coding Steering Committee (MCSC)