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General Microbiology & Immunology (PM 401) Second level Semester 4 2024/2025
Characteristics of T Cells
Type Cytotoxic T Helper T cell
CD marker CD8+ CD4+
Effector Form T C cell T H cell
Effector Induces target cell to undergo Activates target cell
Function apoptosis
Potential All nucleated cells B cells, macrophages
Target Cell
Antigen Peptides presented by MHC Peptides presented by MHC
Recognition class I molecules class II molecules
Source of Endogenous Exogenous
Antigen (Produced within the target cell) (produced outside of the target cell)
Activation of B cells
After formation and maturation in the bone marrow, the naive B cells move into
the lymphatic system to circulate throughout the body. In the lymphatic system,
naive B cells encounter an antigen, which starts the maturation process for the B
cell.
B cell activation in adaptive immunity involves these key steps:
General Microbiology & Immunology (PM 401) theoretical handbook Page 125
