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386 PARTE II, SECCIÓN 6 TRASTORNOS METABÓLICOS Y ENDOCRINOS
Vanadil-sulfato, 2,5 a 10 mg/día. Ginseng americano, 1 g antes de las comidas
B B 2 2 cada 8 h. B B 2 2
Picolinato de cromo, 200 a 1.000 μg/día.
®
B B 2 2 Metformina (Glucophage ), 500 a 2.500 mg
L-arginina, 500 a 2.000 mg/día, cada mañana o cada 12 h. A A 2 2
administrados con el estómago vacío.
C 2 2
Rosiglitazona (Avandia ), de 2 a 4 g cada
®
mañana o pioglitazona (Actos ), 15 a A A 2 2
®
■ Fitoterapia/fármacos 45 mg cada mañana.
Los individuos con riesgo elevado pueden
tratarse más apropiadamente con un
fitofármaco o un fármaco.
14. Mokdad AH, Ford ES, Bowman BA, et al: Prevalence of obesity,
Dado que la RI es un proceso continuo que va desde un diabetes, and obesity-related health risk factors, 2001. JAMA
diagnóstico de laboratorio hasta el síndrome metabólico y 289:76-79, 2003.
la DM-2, es necesario tratar el problema específico de cada 15. Hu FB, Li TY, Colditz GA, et al: Television watching and other
paciente. A medida que avanza la enfermedad, están sedentary behaviors in relation to risk of obesity and type 2 diabetes
indicadas más intervenciones terapéuticas. Incluso el 16. mellitus in women. JAMA 289:1785-1791, 2003.
The Diabetes Prevention Program: Design and methods for a clinical
paciente que consigue realizar los cambios con éxito deberá trial in the prevention of type 2 diabetes. Diabetes Care 22:623-634,
vigilarse de por vida, con apoyo emocional y médico 1999.
constante. Son apropiadas las determinaciones periódicas 17. Surwit RS, van Tilburg MA, Zucker N, et al: Stress management
de los indicadores de laboratorio de inflamación, lípidos, improves long-term glycemic control in type 2 diabetes. Diabetes
glucemia, insulina, etc. Care 25:30-34, 2002.
18. Bland J: personal communication, 1996.
19. Knoops KT, de Groot LC, Kromhout D, et al: Mediterranean diet,
lifestyle factors, and 10-year mortality in elderly European men and
women: The HALE project. JAMA 292:1433-1439, 2004.
20. Esposito K, Marfella R, Ciotola M, et al: Effect of a Mediterranean-
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