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1st Int. Transborder Conf. of the Timor Island: Timor %u2013 Science without borderDili, 7-8 May 2025135Neglected and stigmatized disease: Morbus Hansen in 37 Years Old Male: A Case reportG. K. Widyantoro1*, Ch. O. Lada1*, S. E. Nubatonis2, N. E. Handoyo1, E. L.S. Setianingrum1, D. M. Wijaya1and D. Noviyanti11Faculty of Medicine and Veterinary Science, Universitas Nusa Cendana, Indonesia2Bakunase Public Health Centre, Kupang City, East Nusa Tenggara, Indonesi*Corresponding authors: gregoriuskenang77@gmail.com; christinalada@staf.undana.ac.idAbstractHansen%u2019s disease, also known as leprosy, is a chronic granulomatous infectious disease caused by Mycobacterium leprae and Mycobacterium lepromatosis, primarily affecting the skin and peripheral nervous system.1 Individuals who live in close contact with leprosy patients are at higher risk, most likely through infectious aerosols produced by coughing or sneezing, or through prolonged skin-to-skin contact.2 Casual contact%u2014such as shaking hands, hugging, sitting next to someone, or sharing meals%u2014does not lead to transmission.3,4 Case presentation. 37 years old, male, patient found after periodic community screening by Bakunase Public Health Center, Kupang city. Patient suffers from symptoms of decreased visual acuity for 6 months, after having painless and progressive amputation of his distal fingers in both hands and feet. The patient previously had swelling in numerous places %u2014 face, both of the earlobes %u2014 and continued by numbness in most areas on distal surface of limbs within 4 years after working in Ambon as fisherman around 2004, alongside with a colleague suspected with the same symptom. There are telltale signs of multiple hyper-pigmented, well-defined macular and plaque lesions with irregular shapes distributed bilaterally and asymmetrically on the palms, fingers, wrist flexors, arms, elbows, lower legs, feet, and between toes. Sensory loss to pinprick and temperature noted. Bilateral loss of lateral eyebrows (madarosis) and eyelashes, alongside corneal calcification%u2014 suggestive of leprosy involvement. The patient was diagnosed with Morbus Hansen earlier in 2024 after ziehl-neelsen coloring revealed such findings. Patients treated with Fixed Drug Combination for multibasiler regiment for 12 months consisting of Rifampicin, dapsone, and clofazimine, started in early February of 2024. The conclusion is that this case highlight the advanced clinical manifestations of multibacillary Hansen%u2019s disease, including neuropathy induced amputation, extensive cutaneous lesions, sensory loss, and ocular complications, due to delayed diagnosis and treatment. It underscores the importance of early recognition, especially in endemic regions, and the need for continued public health efforts in surveillance, education, and timely management to prevent irreversible disabilities and reduce transmission.Keywords: Morbus Hansen, Neglected disease, Leprosy related disability.