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;
                                                                                         Ar
                                                               Oguh et al.; AJBGE, 2(3): 1-18, 2019; Article no.AJBGE.53356
                                                                                          ticle
                                                                                              no.



                    of  course,  detrimental  to  the  organism.  The
                                                                                                 g

                    o f   cour s e ,    d e tr im e n ta l   to    the   organ i s m.   Th e   fungicides  are  active  only  as  a  coating  on  the e

                                                                                                      th
                                                                                          a
                                                                                            c
                                                                                                n
                                                                                                    n
                                                                                             oa
                                                                                       as
                                                                                                   o

                                                                                               ti
                                                                 urf
                                                                        f
                                                                          the
                                                                s
                                                                       o
                                                                   ace
                                                                                             ot

                                                                                            n
                                                                                         do
                                                                                    a


                                                                                  s
                                                                                     nd
                    nervous  system  is  sensitive  to  these  changes

                                                                              plant
                    n e r v o u s   s y ste m   is    sen si t i v e   t o   these    changes    surface  of  the  plants  and  do  not   fight  back
                                                                 row
                                                                                       lan
                                                                g
                                                                                                .
                    b e c a u s e   glut amic  acid  i s  a n   im p o rtan t   transmitt er    growing mycelia inside the plant tissue.
                    because glutamic acid is an important transmitter
                                                                                          t t
                                                                                               e
                                                                                      p
                                                                              n
                                                                               si
                                                                                           issu
                                                                          elia i
                                                                         c
                                                                        y
                                                                    in
                                                                                    t
                                                                                    he
                                                                     g m
                                                                                de

                                              d
                                           alle
                                                  g
                                                    ta
                                                      minergic
                                                   l
                                                   u
                    substance   in   the   so-called     glutaminergic
                                          c
                        ps


                    sy
                                                   y
                                d
                                                  r
                                                            t
                                                         rtan
                                      um
                                     ci
                                   al
                      na
                                                     i
                                  c
                                                     mpo
                              an
                                          i
                                                v
                            ,

                                             a
                           s
                    synapses,  and  calcium  is  a  very  important     3.9.1 Carboxin mode of action
                                           s
                                                 e
                          e
                                                      t
                    mediator  of  the  impulses.  Furthermore,  the  halt
                                                          h
                                                           alt
                                                       he
                                      lses

                                         .
                                                rmore,
                                           Furthe
                                      d
                             en
                           c
                               e
                                rg
                                                                Carboxin inhibit the dehydrogenation of succinic
                                    o
                                 y
                      aero
                     f
                                   pr
                          b
                           i
                                       u
                                        c
                                                  h

                    of aerobic energy production is very harmful.   C arboxi n   i nh ibit  th e   d eh y d r oge n a ti o n   of  suc c i nic
                                                 y
                                                    r
                                         ion
                                                   a
                                         t
                                                     mful.
                                             s ve
                                             i
                                                r
                    o
                                                                a c id    t o    f u mar ic   aci d ,   an    i mp o r t a n t   st e p    in    t he
                                                                acid  to  fumaric  acid,  an  important  step  in  the
                                                                                          o
                                                                                            ici
                                                                                         t
                                                                                                o
                                                                                           x
                                                                                  e.
                                                                                                  animals


                                                                                     Th
                                                                                             t

                                                                                              y
                    3.9 Carboxin                                tricarboxylic  acid  cycle.  The  toxicity  to  animals
                                                                                                t
                                                                                       e

                                                                a n d  pl a n t s   i s   lo w  in  s p it e   o f  this  ve r y   f u n d a me nt al
                                                                and plants is low in spite of this very fundamental
                                                                                       id
                                                                                 fu
                                                                                        es
                                                                                   ngic
                                                                                                        e
                    C arbo x i n   i s  a   s y stem ic   p e s ti c i de   i s  taken  u p  b y   mode of action. The fungicides in this group are
                    Carboxin is  a  systemic pesticide is taken  up by
                                                                  d
                                                                                             t
                                                                                                   up


                                                                   e

                                                                                                  o
                                                                                                 g
                                                                                                  r
                                                                                               s
                                                                mo
                                                                                             h
                                                                                              i
                                                                          i
                                                                       act
                                                                                                       r
                                                                                           in
                                                                          on.
                                                                      f
                                                                                                      a
                                                                     o
                                                                              The

                                                                                           ma
                                                                                                  r
                                                                                                c
                                                                                          o
                                                                                                 a
                                                                                             t
                                                                                                      y
                                                                                                       ic
                                                                                              ic

                                                                                                       l
                                                                                                   box
                                           nd
                                               m
                                                ay
                                     te
                                       cts
                                          a
                                                     l
                                                       sucki
                                                           ng

                                                   k
                                                    il
                                    o
                        r
                         g
                          an
                    t the  organism  it  protects  and  may  kill  sucking     anilides  of  unsaturated  or  aromatic  carboxylic
                    he
                       o
                                it
                                  p
                                   r
                            i
                             s
                              m
                                                                 n
                                                                          un
                                                                            sat
                                                                               urat
                                                                a
                                                                     s
                                                                  lide
                                                                  i
                                                                       of

                                                                                     or
                                                                                        a
                                                                                   d
                                                                                  e
                                                                                         r
                    aphids or the growing fungal hyphae. The older
                    a p h ids   o r    the  gro wing   fun g a l   h y ph a e .   T h e    old er    acids.



                                                                     em
                                                                   ne

                                                 ps in
                                                e
                                                               n
                                                       reparatio
                                                      p
                                            4. St
                                        Fig. 4. Steps in preparation of neem seed solution
                                        Fi
                                          g
                                                                 of
                                           .



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