Page 151 - DUOKOPT BIBLIOBOOK
P. 151

EFFICACY









                 COMPARISON OF THE EFFECTS OF DORZOLAMIDE/TIMOLOL

                  AND LATANOPROST/TIMOLOL FIXED COMBINATIONS UPON

                   INTRAOCULAR PRESSURE AND PROGRESSION OF VISUAL

                     FIELD DAMAGE IN PRIMARY OPEN-ANGLE GLAUCOMA.





                                            Pajic B, et al. CMRO. 2010 Sep;26(9):2213-9.





                 ABSTRACT


                 PURPOSE: To report the long-term effect of the DTFC and LTFC on IOP and visual field defects over
                 time in naive POAG patients.


                 METHODS: Prospective, 4-year, open-label, interventional study with 178 patients having visual field
                 defects related to newly diagnosed untreated POAG.


                 STUDY CRITERIA: IOP mesurements (mm Hg)


                 RESULTS: Mean IOP reduction was from 22.6 +/- 3.0 to 13.8 +/- 1.9 mmHg with DTFC and from 22.3
                 +/- 4.0 to 14.7 +/- 1.9 mmHg with LTFC





















                 CONCLUSIONS Key messages
                 ‐     DTFC seems to be effective in preventing glaucomatous visual field progression.
                 ‐     DTFC is as efficient as LTFC in reducing IOP.










                                                                                                                   151
   146   147   148   149   150   151   152   153   154   155   156