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Health Care
         Date                 November 20, 2025      Health Care
         52wk High                        $2.82
         52wk Low                         $0.95      Aytu BioPharma, Inc.                     AYTU        $2.00
                                                     Denver Corporate Center III
                                                     Denver, CO 80237

                                 (USD - in millions)  aytubio.com
         Market Cap                        20.4
         Enterprise                        16.1
         Basic Shares Out.                10.19      COMPANY OVERVIEW
         Float                             7.04
         Institutional Holdings           9.99%      Detailed Analysis:Channelchek.com
         Short Interest                    0.50
         Avg. 90-Day Volume                0.18      Aytu is a pharmaceutical company focused on advancing innovative
                                                     medicines for complex central nervous system diseases to improve the
                                                     quality of life for patients. The Company’s prescription products include
                                                     EXXUA (gepirone) extended-release tablets (see Full Prescribing
         EPS Data                                    Information, including Boxed WARNING) for the treatment of major
                                                     depressive disorder (MDD), Adzenys XR-ODT® (amphetamine)
                       2022      2023      2024      extended-release orally disintegrating tablets (see Full Prescribing
         CQ1         (35.80)    (1.93)    (0.52)     Information, including Boxed WARNING) and Cotempla XR-ODT®
         CQ2          (7.00)    (0.59)    (0.82)     (methylphenidate) extended-release orally disintegrating tablets (see
                                                     Full Prescribing Information, including Boxed WARNING) for the
         CQ3          (1.20)    (1.48)    (0.15)     treatment of attention deficit hyperactivity disorder (ADHD), and a line
         CQ4          (2.15)    (0.04)     0.13      of legacy products, including Karbinal® ER (carbinoxamine maleate),
         CY          (46.15)    (4.04)    (1.36)               ®              ®             Source: Channelchek/QuoteMedia




         Long-Term EPS Estimate             N/A
         Price/Book (mrq)                   2.34
         ROE (ttm)                        -50.23
         Debt-to-Total Cap. (mrq)         55.07
         Fiscal Year End                 30-Jun

                                                     Denver Corpo Denver             CO              80237

         Key Executives
         CEO:      Disbrow, Joshua
         CFO:      Selhorn, Ryan
         COO:      Cabano, Margaret
         IR:       N/A
                                                             Noble Capital Markets, Inc.
         Source: Capital IQ, Noble Financial estimates, company filings
         Noble Senior Analyst                                561-994-1191   noblecapitalmarkets.com
         Robert LeBoyer                                      MEMBERS: FINRA, SIPC, MSRB
         rleboyer@noblelsp.com                               Following the conference, complete video library of presentations will be
                                                             available at: channelchek.com | nobleconference.com
         (212) 896-4625


         Refer to the back of the book for disclosures
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