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Incubation period is 10-90 days. The chancre appears as a solitary, non-tender

                   indurated ulcer. In 10% of case more than one chancre is present. The chancre

                   usually health after 1-6 weeks. The inguinal glands enlarge. When the lesion is on

                   the vulva or lower vagina. They are hard, not tender and do not suppurate.







































                                   Fig.,( 44 ) Primary Syphilis chancre adopted from



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                   age.slideserve.com%2f456565%2fprimary-syphilis-chancre-
                   l.jpg&ehk=UKwwar%2b08uu%2f8VIav7Y%2bGdDPiVKOXEA5e0h172K%2fUEQ%3d&risl=&pid=ImgRaw&r=0

                   Secondary stage


                         If untreated, the manifestations of secondary syphilis appear in 6 weeks to 6

                   months after healing of the chancre. These result from entry of spirochetes into the

                   bloodstream and include pyrexia, condylomas, generalized lymphadenopathy and

                   occasional loss of scalp hair. The condylomas appear as flat wart-like growths in

                   the vulva and around the anus. Sometimes the secondary lesions appear before




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