Page 1066 - The Toxicology of Fishes

1046 The Toxicology of Fishes

cholinergic, 431 New Bedford Harbor, 366, 611–616, 623–624
development, 418–420, 425, 442 Newark Bay, New Jersey, 611
in zebrafish, 419 NF-1, 561
parasympathetic, 423 NF-κB, 197, 287
peripheral, see peripheral nervous system NF-κB essential modulator (NEMO), 899
somatic, 422 Nibea mitsukurii, 561
sympathetic, 423 nickel, 11, 31, 404, 606
nervous system sensitivity, 814; see also central smelting, 440
nervous system nicotinamides, 283
netting, xenobiotic kinetics and, 79 nicotine, 300, 432, 434
neural cell adhesion molecules (NCAMs), 561 nicotinic acetylcholine receptors, 435, 444
neural crest cells, 418 nicotinic receptors, 432, 434
neural folds, 418 nifedipine, 172, 173, 355
neural induction, 418 nitrenium ion, 207
neural keel, 418 nitric oxide, 276, 421, 422, 423, 544
neural plate, 418 nitric oxide synthases (NOSs), 276, 298
neuroectoderm, 418, 419 nitrification, 11
neuroendocrines, 458, 460, 462, 467, 475, 477, nitroaromatics, 179, 298
491 nitrobenzene, 79
secretion of, 467–468 p-nitrobenzoic acid, 179
neurofibromatosis, 561 nitrobutyl chloride (NBC), 194
neurofibromin, 561 2-nitrofluorene, 179
neuronal nitric oxide synthases, 276 nitrofurantoin, 179, 296, 546
neuronal specification, 425 nitrogen, 287, 603, 743
neuronopathies, 426 nitrogen dioxide, 298
neuropeptide Y, 421, 423 nitrogen excretion, 13
neuropeptides, 423, 475 8-nitroguanine, 545
neurotoxicants, 425, 427, 428, 429–445, 601 nitromethane, 571
aluminum, 441 4-nitrophenol, 184, 187, 188, 375
cholinergic, 433 p-nitrophenol, 168, 204
cholinesterase inhibitors, 431–434 4-nitroquinoline 1-oxide, 179
developmental, 425, 439, 441 nitroreductases, hepatic, 179
ethanol, 439–440 nitrosamines, 154, 538, 572
lead, 441 N-nitrosodiethylamine, 365
locomotion, and, 428, 433 nitrosopyrrolidine, 572
metals, 440–443 nNOS, 276
narcotics, 429–431 nocodozole, 365
neurotoxins, 443–445 nodular proliferation, 572
organochlorine insecticides, 437–439 N-OH-AAF, 542
pyrethroid insecticides, 434–437 noncompartmental models, 92, 124–126
neurotoxicity, 417–445, 829, 831, 838 nongenomic steroid actions, 465–466
developmental, 425, 437 non-point-source discharges, 440, 685
manifestations in fish, 426–428 nonpolar compounds, 57, 60
mechanisms of, 425–426 nonspecific cytotoxic cells (NCCs), 490, 493, 496,
neurotoxins, 443–445 502, 503, 509, 512
neurotransmitters, 200, 258, 295, 422, 423, 424, nonylphenol, 173, 175, 189, 204, 469, 473, 702,
425, 426, 427, 435, 438, 439, 440, 441, 442, 988, 989, 990, 991, 992
467, 468, 475, 477, 495 4-nonylphenol, 203, 355
catecholaminergic, 422 nonylphenol carboxylates (NPECs), 989, 991
monoamine, 458 nonylphenol diethoxylate, 365
telencephalon, 421 nonylphenol ethoxylates (NPEOs), 988, 989, 991
neurotrophins, 439 nonylphenoxy carboxylic acids, 989
neutrophils, 276, 278, 494, 502, 510 no-observable-adverse-effect level (NOAEL), 808