Page 1068 - The Toxicology of Fishes
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1048                                                       The Toxicology of Fishes


                       Opsanus beta, 43                         organophosphorus esters, 427, 432
                       Opsanus tau, 329, 349, 694               organoselenides, 178
                       optic nerve, 421, 424                    organosomatic indices, 703, 706
                       optic tectum, 421, 424, 443              organotin, 199, 440
                       oral administration, 94, 102             organotins, 199, 357, 440, 503
                       oral bioavailability, 17, 71, 75, 94, 102, 114, 126  ormetroprim, 79
                       oral mucosa, 79                          Oryzias latipes, 162, 177, 178, 214, 237, 341, 343,
                       oral valve, 65                                363, 430, 433, 434, 436, 437, 439, 445, 490,
                       ore body, 783                                 498, 500, 503, 504, 505, 506, 509, 511, 512,
                       Oreochromis mossambicus, 329; see also tilapia  513, 557, 558, 560, 564, 565–566, 569, 711,
                       Oreochromis niloticus, 189, 331, 355, 490, 495,   842, 974, 990; see also medaka
                           496, 498, 503, 505, 507, 508, 511, 512, 848;   Oscillatoria, 444
                           see also tilapia                     Osmerus mordax, 826
                       organ mass, 706                          osmolarity, 401, 411
                       organelles, 375                          osmoregulation, 13, 28–29, 31, 56, 65, 69, 177,
                       organic anion transporter polypeptides (Oatps),   401–411, 440, 442, 476, 707, 809, 813, 829
                           63, 85, 361, 362–363                     endocrine control of, 410–411
                       organic carbon, see carbon: organic      Ostα, Ostβ, 363
                       organic carbon–water partition coefficient (K ),   Osteichthyes, 422
                                                         oc
                           12, 17, 130, 131, 678, 884           Ottawa River, 847
                          benzo(a)pyrene, 43                    ovarian atresia, 895
                          PAH, 882                              ovarian follicles, 458
                       organic cation transporters (OCTs), 361, 362  ovarian somatic index, 831
                       organic compounds, 129, 469, 947         ovaries, 81, 82, 123, 357, 460, 465, 471, 473
                          chemical extraction efficiencies of, 15   CYP3A expression in, 174
                          chlorinated, 934, 937, 944, 949       ovipositor formation, in males, 951
                          copper, and, 30                       ovulation, 461, 471
                          dietary uptake data for, 17           oxalic acid, 283
                          dissolved, 28                         oxidants, 286
                          ionized, 67                           oxidation, 154–179, 191, 281, 349, 360, 540,
                          lipophilic, 16                             544–547, 810, 954
                          methylmercury, and, 39                    fatty acid, 349, 357
                          nonionic, 12                              lipid, 342
                       organic extracts, of lake trout, 837–838     protein, 293–294
                       organic matter, 28, 30, 38                   saturated fat, 342
                       organochlorine, 134, 372, 437–439, 504,   oxidative phosphorylation, 441
                           506–507, 563, 661, 937, 944          oxidative stress, 5, 164, 190, 194–195, 236, 258,
                          insecticides, 80, 808                      273–308, 372, 439, 441, 442, 476, 545, 547,
                          pesticides, 11, 12, 467, 468, 475, 476, 601,   690, 693, 694, 696
                               625, 626–627, 824, 825               adaptation to, 305
                              tolerance to, 608–609                 aging, and, 295
                          -resistant fish, 609                      biomarkers of, 305–307
                       organogenesis, 250                           cancer, and, 307
                       organomercury seed treatments, 440           chemical-mediated, 298–300
                       organometals, 11, 12, 20, 35–39, 115, 497    diseases associated with, 295
                          accumulation of, 35                       fish studies, 301–307
                          speciation of, 35                            antioxidant defense systems, 301–303
                       organophosphate esters, 213–215                 in vivo prooxidants, 303
                       organophosphate pesticides, 305, 702         iron-induced, 441
                       organophosphates, 182, 207, 432, 433, 497,   oxides, 37
                           504–505, 609, 735, 807, 810          oxidoreductase, dicoumarol-sensitive, 179
                          metabolites of, 213                   8-oxo-deoxyguanosine (8-oxo-dG), 545, 546, 547
                       organophosphorus, 431, 433–434, 467      oxolinic acid, 73, 75
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