Page 1071 - The Toxicology of Fishes

Index 1051

organophosphate, 433, 497, 702, 735 phenanthrenequinone, 179
organophosphorus, 467 phenobarbital, 166, 173, 182, 188, 257, 354, 356,
tin in, 503 541
Petersen mark–recapture method, 795 phenobarbital response elements (PBREMs), 166
petroleum, 440, 603 phenol red, 106, 120
feeding rates, and, 428 phenol sodium azide, 673
petroleum hydrocarbons, 376, 928 phenolate ions, 24, 26, 28
Petromyzon marinus, 567, 568, 820, 823, 849, 856 effects of on phenol bioavailability, 25, 26,
Pfiesteria piscicida, 444 27
P-glycoprotein (Pgp), 63, 84–85, 361, 362, 363, permeability, and, 25, 26, 27, 28
365, 366, 378, 604, 606, 620, 691–692, 712 phenolics, chlorinated, 944
overexpression of, 608 phenolphthalein, 86
transporters, 619 phenols, 20, 65, 76, 79, 122, 184, 185, 200, 202,
pH, 30, 60, 129, 428, 430, 439, 799, 807 204, 205, 207, 208, 296, 430, 603, 618, 662,
ammonia toxicity, and, 23, 24 937
arterial blood, 445 bioavailability of, 24–28
association constants, and, 34 chlorinated, 188, 937
blood, 62, 83, 707 elimination of, 28
chemical concentration, and, 61 pH, and, 24–28
dissociation, and, 12 pK of, 25
a
epoxides, and, 180 planar, 184, 186, 187, 188
gill, 14 speciation of, 28
carbon dioxide, and, 23 substituted, 82
gradients, 73 un-ionized, 25, 26, 27, 28
intestinal, 73 uptake of, 24, 25, 26, 27, 28
LC values, and, 21, 23, 24 phenylacetic acid, 206
50
luminal, 70 phenylacetyl-coenzyme A, 206
mercury release, and, 38 phenylacetyltaurine, 206
methylmercury–DOC binding, and, 38 phenylalanine, 294
optimum, for enzymatic activities, 176 phenylglucuronide, 122
optimum, for microsomal epoxide hydrolase phenylhydrazine, 691
activity, 180 phenylmercury, 36
pentachlorophenol, and, 24–25 phenylsulfate, 122
phenols, and, 24–28 pheromones, 76, 186, 188, 467
physiological, 199, 205, 206, 278, 283, 360 PHGPX, 280
pK values, and, 12 phorbol myristate acetate (PMA), 500
a
seminal fluid, 461 phosphates in Great Lakes, 821
stomach, 73 phosphatidylcholine, 292
trichlorophenol, and, 27 phosphatidylinositol 3-kinase/Akt, 466
uptake rate constants, and, 27 3′-phosphoadenosine-5′-phosphosulfate (PAPS),
phagocytes, 287, 295, 301 199, 202, 205
phagocytosis, 276, 342, 494, 495, 500, 503, 508, phosphodiesterase, 441
510, 512 phosphoenolpyruvate carboxykinase (PEPCK),
phagosomes, 409 691
phalloidin, 365 phospholipase A , 463
2
pharmaceuticals, 169 phospholipase C (PLC), 463
pharmacokinetics, 56 phospholipid hydroperoxide glutathione
phase I enzymes, 154–182 peroxidases, 280
phase II enzymes, 160, 183–207 phospholipids, 119, 187, 292
phase II metabolic pathways, 62 membrane, 405
phase transitions, 57 metabolism of, 440
phenamel, 404 phosphorothionate, 213, 214
phenanthrene, 42 phosphorus, 432, 743