Page 1075 - The Toxicology of Fishes

Index 1055

cytochrome P450, 162 vitelline envelope, 976
cytoskeletal, 365 yolk precursor, 353, 460, 469, 690
cytosolic, 190, 191 zinc finger, 258
direct reversal repair, 549 zona radiata, 460
DNA repair, 561 protein kinase, 557
DNA binding, 160 protein kinase A (PKA), 463
eggshell membrane, 348 protein kinase C, 461, 462, 463
FMO-like, 176, 177 protein serine kinases, 558
free, 80 protein thiols, 35
globular, 60 protein threonine kinases, 558
green fluorescent (GFPs), 251 protein tyrosine kinases, 555–557
helix–loop–helix, 160 proteomics, 251–253, 259
heme-containing, 154 protoporphyrin IX, 157
hepatic, CAR-immunoreactive, 166 proximal tubule, 88, 361
hepatic, CYP2B immunoreactive, 164–166 Pseudomonas aeruginosa, 296
immunoreactive, 162, 164–166 Pseudopleuronectes americanus, 213, 557, 576;
inducible, 688–694 see also white flounder, winter flounder
Keap1, 289, 290 pseudoreplication, 739
liver, 348, 505 Ptychodiscus brevis, 443, 444
macromolecular, uptake of, 63 pufferfish, 166, 167, 168, 173, 176, 184, 351, 353
mediator, 353 Fugu rubripes, 155
membrane, 191 CD4 T-cell homologs in, 567
membrane-bound signal transduction, 561 c-fos in, 559
metabolism, 441, 475 CYP1A, 162
metal-binding, 120, 606, 610 interleukins, 494
metallothionein, 286 NF-1 in, 561
metallothionein-like, 611 genome, 358
multidrug resistance-associated (Mrps), 63, nuclear receptor genes in, 353
84 peroxisome proliferator-activated receptors
Mx, 493 in, 357
NRF2, 258 pregnane X receptor in, 355
Nrf2-binding, 289 Takifugu rubripes, 251
O -carrying, 277 Tetraodon nigroviridis, 251
2
overexpression, 608 vitamin D receptor in, 356
oxidation, 191, 293–294 WT-1 homolog in, 560
peroxidation, 468 Puget Sound, 6, 182, 208, 510, 534, 575, 694, 695,
Pgp-like, 366, 606 710
phosphorylation, 441 bottomfish, 890–892, 902, 912
plasma, 65, 79, 88, 92, 93, 94, 95, 96, 97 characteristics of, 878–880
–protein interactions, 353 Chinook salmon in, 899
receptor, 244, 249 damage assessment, 908–911
recombinant, 169 English sole in, 888, 890, 890–892, 894–897,
residues, 194 899, 901
sex-steroid-binding, 460 fish populations, 878–880
soluble, 606 flatfish, 886, 889
solvent-aggregated, 247 other contaminants in, 881–882, 908
steroidogenic acute regulatory, 459 Pacific herring in, 897
stress, 690–691 Pacific Northwest salmon in, 897
synthesis, 330 polycyclic aromatic hydrocarbons in, 877–912
tau, hyperphosphorylated, 441 sources of, 881
transport, 78, 80, 84, 85, 120 salmon in, 892–893, 897–901
transporter, 362 sediments, 881
upregulation of, 604 starry flounder, 891