Page 1072 - The Toxicology of Fishes
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1052                                                       The Toxicology of Fishes


                       phosphorylate esterase, 431              placenta, 37, 69, 82, 361, 556
                       phosphorylation, 287, 289, 432, 435, 441, 464,   plaice (Pleuronectes platessa), 162, 163, 184,
                           496, 503, 555, 827                        187, 188, 194, 289, 494
                          inhibitor, 365                            antioxidants, and, 213
                       phosvitin, 460                               butylated hydroxyanisole exposure, 198
                       photoactivation, 605                         ceruloplasmin in, 286
                       photoaffinity ligand, 247                    glutathione S-transferase in, 192, 692
                       photodegradation, 603                        GST-A4 in, 194
                          methylmercury, 37                         liver
                       photolyase, 549, 550                            cytosolic glutathione S-transferase, 199
                       photomodification, 300                          UGTs in, 188
                       photooxidation, of metallic mercury, 36  planar aromatic compounds, 693
                       photoperiod, 458, 460                    planar aromatic hydrocarbons, 692, 694
                       photoreduction, of divalent mercury, 36  planar halogenated aromatic compounds, 696
                       photosensitivity, 300, 424               planar halogenated aromatic hydrocarbons
                       phototoxicity, 303                            (PHAHs), 253, 256, 299
                          benzo(a)pyrene, 44                        resistance to, 366
                       Phoxinus phoxinus, 442                   planar polychlorinated biphenyl, 826, 837, 839,
                       phthalate ester plasticizers, 198, 257, 352   846
                       phthalate esters, 470                        congeners, 822, 835
                       phthalate monoesters, 357                planar phenols, 188
                       phthalates, 188, 476, 983                planar polyaromatic phenols, 186
                       Physical Habitat Simulation Model, 797   planktivores, 132–134
                       physiological acclimation, 598, 610      plankton, 132, 737, 929
                       physiological inputs, 118–119                fish predation, and, 743
                       physiologically based models, 91–92, 97  plant toxins, 444
                       physiologically based pharmacokinetic (PBPK)   plasma, 78, 92, 94, 95, 97
                           models, 657                              concentration, 78, 85, 95, 99, 102, 103, 104,
                       physiologically based toxicokinetic (PBTK)       105, 125
                           models, 105–126, 129, 133                concentration–time curve (AUC), 17, 125,
                       phytoalexins, 194                                126
                       phytoestrogens, 203, 476, 983                binding, 61, 79, 88, 90, 92, 93, 94, 95, 96, 97,
                       phytoplankton, 13, 30, 132, 356, 737             118
                          methylmercury uptake by, 37               ion concentrations, 702
                       phytosterols, 468, 937, 957                  membrane, 84, 85
                       picrotoxin, 438, 439                         proteins, 61, 65, 79, 88, 92, 93, 94, 96, 97
                       pigment cells, 76                            samples, number of, 99
                       pike, see Northern pike                      xenobiotic transport in, 79–80
                       Piles Creek, 621–622                     plastic stabilizers, 441
                       Pimephales promelas, 348, 430, 433, 443, 445,   plasticizers, 983, 992
                           611, 734, 735, 950, 950–951, 974; see also   platelet-derived growth factor (PDGF), 557
                           fathead minnow                       Platichthys flesus, 177, 508, 509, 560, 692, 981;
                       pineal organ, 421                             see also flounder
                       pinfish (Lagodan rhomboides), 166        Platichthys stellatus, 212, 890, 891; see also starry
                       pink salmon (Oncorhynchus gorbuscha), 897     flounder
                          mutations in, 698                     platyfish, see Xiphophorus
                          oil-exposed, 558                      Pleuronectes americanus, 166, 172, 362, 512,
                       pinocytosis, 63, 477                          827; see also winter flounder
                       piperonylbutoxide, 42                    Pleuronectes bilineata, 891; see also rock sole
                       piscivores, 37, 38, 132–134              Pleuronectes platessa, 162, 194, 198, 289, 494,
                       pituitary, 410, 421, 458, 460, 465, 467, 475, 476,   692; see also plaice
                           702, 711                             Pleuronectes vetulus, 212
                       pK , 12, 25, 27, 61, 62, 199             pleuronectid flatfish, 196
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