Page 1238 - Small Animal Internal Medicine, 6th Edition

1210 PART X Joint Disorders

VetBooks.ir Drugs Used in Joint Disease—cont’d RECOMMENDED DOSE

DRUG NAME (TRADE
NAME) PURPOSE DOG CAT
Cefotaxime Antibiotic 20-40 mg/kg IV q6h Same
Ceftriaxone Antibiotic 25 mg/kg, IV or SC, q24h Same
Cephalexin (Keflex) Antibiotic 20-40 mg/kg PO q8h Same
Chlorambucil (Leukeran) Immunosuppression 0.1-0.2 mg/kg PO q24h initially, 0.1-0.2 mg/kg PO
then taper to every other day q24-72h or 2 mg/cat
once a response is seen q48-72h
Chondroitin sulfate Chondroprotective 15-20 mg/kg PO q12h Same
Colchicine Antiinflammatory 0.03 mg/kg PO q24h Same
2
Cyclophosphamide (Cytoxan) Immunosuppression 50 mg/m PO q48h Same
Cyclosporine (Atopica) Immunosuppression 2.5-5 mg/kg PO q12h Same
Deracoxib (Deramaxx) Analgesia 1-2 mg/kg PO q24h None
Antiinflammatory
Doxycycline Antibiotic 5-10 mg/kg PO, IV q12h Same
Enrofloxacin (Baytril) Antibiotic 5-20 mg/kg PO or SC q24h or 5 mg/kg PO or SC
divided q12h q24h; use
pradofloxacin
Etodolac (Etogesic) Analgesia, antiinflammatory 10-15 mg/kg PO q24h None
Firocoxib (Previcox) Analgesia, antiinflammatory 5 mg/kg PO q24h None
Gabapentin (Neurontin) Analgesia 2-10 mg/kg PO q8-12 h 2-10 mg/kg PO q8-24 h
Glucosamine Chondroprotective 15-20 mg/kg PO q12h Same
Leflunomide (Arava) Immunosuppression 3-4 mg/kg PO q24h 10 mg/cat q24h
Meloxicam (Metacam) Analgesia, antiinflammatory 0.2 mg/kg PO once, then 0.05-0.1 mg/kg q24h ×
0.1 mg/kg PO q24h maximum 4 d then
0.1 mg/cat/24h
Methotrexate (Rheumatrex) Immunosuppression 2.5 mg/m PO q48h Same
2
Metronidazole (Flagyl) Antibiotic 10-15 mg/kg PO q8h Same
7.5 mg/kg IV q8h Same
Pentosan polysulfate Chondroprotective 3 mg/kg IM q7d None
(Pentosan 100)
Piroxicam (Feldene) Analgesia, antiinflammatory 0.3 mg/kg PO q48h Same
Polysulfated Chondroprotective 3-5 mg/kg IM q4d for 8 tx, then Same
glycosaminoglycans q30d
(Adequan)
Pradofloxacin (Veraflox) Antibiotic 3-4.5 mg/kg PO q24h (tablets 3-4.5 mg PO q24h
only) (tablets); 5-7.5 mg/kg
PO q24h (oral
suspension)
Prednisolone Immunosuppression 2-4 mg/kg PQ q24h 4-6 mg/kg PO q24h
Prednisone Antiinflammatory 0.5-1 mg/kg PO q24h 1 mg/kg PO q24h
2-4 mg/kg PO q24h 4-6 mg/kg PO q24h;
use prednisolone instead
Antiinflammatory 0.5-1 mg/kg PO q24h Same
Tramadol Analgesia 2-5 mg/kg PO q8-12h 1-5 mg/kg PO q8-12h

IM, Intramuscular; IV, intravenous; PO, oral; SC, subcutaneous; tx, treatments.