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76                             Veterinary Laser Therapy in Small Animal Practice

                                                                          LT has been used in clinical studies with human
                                                                        patients  to  reduce  gingival  inflammation,  decrease

                                                                        dentin hypersensitivity, [227]  and improve mucosal

                                                                        healing after oral surgery. The majority of studies have
                                                                        been performed with low power devices, though, in a
                                                                        variety of protocols (most of them using 2–10 J/cm ),
                                                                                                                    2
                                                                        and sometimes some of the parameters are not spec-

                                                                        ified. Laser improved clinical and biometrical param-
                                                                        eters of mucosal healing after gingivectomy in human
                                                                        patients  with bilateral  procedures in which one side
                                                                        served as control and the other received treatment at
                                                                        4 J/cm .   In a double-blind clinical study in which,
                                                                             2 [228]
                                                                        again, one side served as a control, the addition of LT to
                                                                        scaling and root planing reduced probing pocket depth,
                                                                        plaque, and gingival indices. [229]  In cases with conserva-
                                                                        tive treatment, LT also improved plaque index, gingival
                                                                        index, and bleeding on probing index in a case–control
                                                                        study. [230]  Cytomorphometric  analysis of gingivitis
                                                                        in children improves after LT. [231]  Recent systematic
                                                                        reviews conclude that LT improves management of
                                                                        chronic periodontitis, [232]  mucosal healing, and dental
                                                                        pain. [233]  Sometimes higher doses (not necessarily
                                                                        power, especially if there is high sensitivity) are used for
                                                                        immediate postoperative pain and inflammation treat-

                                                                        ment than for tissue proliferation. [234]
                                                                          LT has also been used in human implantology to
                                                                        improve implant integration. In vitro studies show laser
                     Figure 7.16 (a) This 15-year-old hypothyroid dog shows

                     hyperkeratosis and chronic inflammation of the lateral elbow   can enhance the attachment to the titanium implants

                     skin. (b) The change after two treatments, once a week, with   and proliferation of human gingival fibroblasts in a
                           2
                     4 J/cm  and average power 3 W, was notable.        dose-dependent manner. [235]   In vivo models demon-
                                                                        strate laser increases osteocyte count and viability and
                                                                        accelerates osteogenesis and integration of titanium
                     tissues, whether we are talking about stomatitis, peri-  dental implants, [236]  while reducing the inflammation.

                     odontal disease, or wounds in the oral cavity, all very   [237]
                     frequent conditions presented in canine and feline   Radiotherapy- and chemotherapy-induced oral
                     practice. Of course, gingivitis and/or stomatitis is very   mucositis is a common problem in patients undergo-
                     varied in its causes and usually multifactorial: from   ing oncological  treatment.  There  are several  clinical


                     dental plaque or tooth malposition,  to feline viruses   trials  in humans reporting both  the efficacy [64]  of LT

                     and overreaction of the immune system, among       and the lack of it [238]  in preventing the development of
                     others.                                            mucositis, but once the mucositis appears, LT seems


                        LT as an adjunctive treatment sometimes leads to a   to significantly decrease its duration. [65]  This has many
                     decrease in the need for medication, especially in cats   consequences, including patient comfort among others,
                     with chronic stomatitis, and helps provide better pain   and the possibility of eating better and maintaining a
                     management. Very often you may notice a reduction   better nutritional status. [66, 67]
                     in pain, which translates as a better ability to eat, even   The treatment plan will change according to the

                     without  an improvement in  the  macroscopic  lesions.   affected area, the clinical status, and the handling of

                     Animal clinical studies are missing in this field, but   our particular patient. The gingiva can often be quite


                     let’s have a look at what has been published in human   well exposed in cooperative patients by manipulating
                     medicine.                                          the lips and slightly opening the mouth (Figs 7.17 and








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