Page 415 - Veterinary Immunology, 10th Edition

14.1).
VetBooks.ir

FIG. 14.16 The origins and some properties of IFN-γ.

Box 14.1

Type 1 and Type 2 Immunity

There is a growing tendency among immunologists to classify
protective immune responses into two types. Type 1 immunity
encompasses the use of Th1 cells. However, it also involves the use
of Th17 cells, cytotoxic T cells, group 1 and 3 innate lymphoid cells,

and M1 macrophages, as well as immunoglobulins G, M and A.
Type 1 responses are responsible for immunity to bacteria, viruses,
protozoa and fungi. It employs the cytokines IFN-γ, IL-12, -17, and

-18. Type 2 immunity, in contrast, encompasses the use of Th2 cells.
In addition, it includes group 2 innate lymphoid cells, basophils,
mast cells, eosinophils, M2 macrophages, and immunoglobulin E.
It also employs the cytokines IL-4, -5, -9, -13, -25, -33, and TSLP.

415