Page 416 - Veterinary Immunology, 10th Edition

Type 2 responses are responsible for immunity to parasitic
VetBooks.ir helminths and arthropods as well as for allergic responses (Fig.

14.17).

FIG. 14.17 A comparison of the key features of type 1 and type 2
immune responses.

Interleukin-2

+
IL-2 is produced by activated CD4 Th1 cells. Some is also produced
+
by CD8 cells, NKT cells (Chapter 19), dendritic cells, and mast
cells. Its targets are T, B, and NK cells and macrophages. IL-2 is a
potent stimulator of T cell proliferation, IFN-γ production, and

antibody production by B cells. It enhances the cytotoxicity of CD8 +

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