Page 255 - Traité de chimie thérapeutique 6 Médicaments antitumoraux
P. 255

10. DACARBAZINE ET TEM OZOLOMIDE                        211

              SIEH D. H., MICHEDJAI C. J., Acid-catalyzed decomposition of trialkyltriazenes : pro-
              tected alkyldiazonium ions, J. amer. Chem. Soc., 1981, 103, 442-445.
              SMITH R.J. et al., Specific acid catalysis in the decomposition of trialkyltriaenes, J. amer.
                Chem. Soc., 1984, 106, 1056-1059.
              WILMAN D.E.V. et al., Turner inhibitory triazenes. 3. dealkylation within an homologous
               series and its relation to antitumour activity, J. Med. Chem., 1984, 27, 870-874.
              RAMOS M.N., PEREIRA S.R., Conformation, electronic structure and biological activity
               of antitumour triazenes, J. Chem. Soc., Perkin Trans. Il, 1986, 131-133.
              SMITH R.H., MICHEDJA C.R., A new class of potential chemotherapeutic agents, 3-acyl-
               1,3-dialkyltriazenes, Proceed. Amer. Assoc. Cancer Res., 1987, 28, 1210.
              SMITH R.J. et al., Novel cross-linking alkylating agents, 1-(2-chloroethyl)-3-methyl-3-
               acyltriazenes, J. Org. Chem., 1988, 53, 1467-1471.
              RYNG S. et al., Synthesis and cytostatic properties of 5-substituted derivatives of 3-
               methylisoxazolo[5,4-d]1,2,3-triazine-4-ones and 3-methyl-5-triazene 4-isoxazolecar-
               boxylic acid ethyl esters, Il farmaco, 1997, 52, 105-108.

              TÉMOZOLOMIDE

              ARTICLES GÉNÉRAUX
             THREADGILL M.D., The chemistry of azolotetrazinones, in The chemistry of antitumour
               agents, Wilman D.E.V., ed., Blackie, London, 1990.
             STEVENS M. F.G, NEWLANDS E. S, From triazine and triazenes to temozolomide, Eur.
               J. Cancer, 1993, 29A, 1045-1047.
              NEWLANDS E.S. et al., Temozolomide: a review of its discovery, chemical properties,
               preclinical development and clinical trials, Cancer Treatm. rev., 1997, 23,35-61.
             Temozolomide, Drugs Fut., 1994, 19, 746-749 ; 1995, 20, 860-861 ; 1996, 21, 867-869;
               1999, 24, 944-947 ; 2000, 25, 884-887.

             VOIES D'ACCÈS
              LUNT E. et al., Tetrazine derivatives and pharmaceutical compositions containing them,
               Ger. Offen 3 231 255 in Chem. Abst. 1983, 98, 198285 m.
             STEVENS M.F.G. et al., Antitumour imidazotetrazines.1. Synthesis and chemistry of 8-
               carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3/)-one, a novel broad-
               spectrum antitumor agent., J. Med. Chem., 1984, 27, 196-201.
              HORSPOOL K.R. et al., Antitumour imidazotetrazines.20. preparation of the 8-acid deri-
               vzative of mitozolomide and its utility in the preparation of active antitumor agents, J.
               Mead. Chem., 1990, 33, 1393-1399.
             CLARK A.S. et al.,  Antl-tumour lmldazotetrazlnes.  Part XXI.  Mitozolomlde and
               temozolomide : probes for the major groove of DNA, Anti-Cancer drugs, 1990, 5, 63-
               68.
              LOWE P.R. et al., Antitumour imidazotetrazines. 25. Crystal structure of 8-carbamoy-3-
               methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3.H)-one (temozolomide) and structural com-
               parisons with the related drug mitozolomide and DTIC, J. Med. Chem., 1992, 35, 3377-
               3382.
   250   251   252   253   254   255   256   257   258   259   260