Page 333 - Traité de chimie thérapeutique 6 Médicaments antitumoraux

12. AMIFOSTINE • RADIO- ET CHIMIOPROTECTION 289

en thiol libre hydrosoluble, le 2-mercaptoéthanesulfonate, ou mesna (cf. chapitre 26).
Selon HAUSHEEA et al., un prétraitement par BNP 7787 limite la toxicité du cisplatine et
du carboplatine à forte dose.

0 0
• .S. r
~s· '---"" 's~s~o
O
1 1
NaO ONa
Figure 3 : Structure de BNP 7787

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