Page 24 - Medicinal Chemistry Self Assessment

Section 1 General Self Assessment

1.4 Salts and Solubility

1.4 Author Query Response
1. Some drug molecules can be formulated as either a potassium salt or hydrochloride salt. Evaluate all of
the acidic and basic functional groups in each of the drug molecules drawn below and fill in the grid with

the appropriate information.

OH H
N H 2 N O

CH
H O 3 OCH 3 OH
N H
H Cl
O Arformoterol Baclofen

O
N F CO H
2
H C
3
N O N N
H N N N
N
H N
Irbesartan
Ciprofloxacin

H 3 C CH 3
H O CH 3 H N
OH

NH 2
OH
OH O OH O O

Tetracycline

13