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46     CHAPTER 3



                   though large numbers of organisms are present in the   known cyst stage associated with its life cycle. T. hominis
                   vaginal discharges. Men are usually asymptomatic and     exhibits an undulating membrane as does T. vaginalis.
                   serve as carriers, but may develop a milky discharge and     Differentiating between the two nonpathogenic species,
                   a nonspecific urethritis.                        Trichomonas tenax, which is found in the human mouth,
                                                                    and T. hominis, which is found in the intestine, may be
                   Disease Transmission                             necessary in some cases but both are considered harmless
                                                                    commensal parasites. Rare cases of pulmonary trichomo-
                   Symptoms range from mild to none at all. Women in   niasis have been documented medically and a few cases

                   particular may be asymptomatic but are capable of trans-  of trichomonalempyema (inflammation with body fluids
                   mitting the organism to others. The condition is quite   often found between the pleura) have been reported.

                   contagious and both partners in a sexual relationship   Only T. tenax will be covered here, as it may be
                   should be treated, as reinfection may occur on a regular   necessary to differentiate between T. vaginalis and
                   basis when one partner is asymptomatic.          T. tenax.


                   Laboratory Diagnosis
                                                                    TRICHOMONAS TENAX
                   The diagnosis of infection by T. vaginalis is accomplished
                                                                    T. tenax is primarily found in the mouth and for this rea-
                   by direct observation of motile trophozoites. Because the   son it may be necessary to determine the presence of and
                   organisms may be mistaken for white blood cells, the
                                                                    identification of the organism. The T. tenax organism is
                   sample should be immediately examined upon receipt of   considered a harmless commensal and is frequently found
                   the sample. All body fluids, including urine, vaginal dis-
                                                                    in the tartar (plaque) that has hardened around the teeth.
                   charges, or urethral secretions, should not be allowed to
                   cool before examination occurs. A liquid microbiological
                   media is sometimes used to culture the organism and per-  Morphology
                   manent stained slides are possible but yield a number of
                   false positive and false negative results. Some serological   The trophozoite of  T. tenax is similar to other
                   tests are available but are not widely used.     trichomonads, particularly when compared with
                                                                    T.  hominis, with the exception that it is more slender.
                                                                    This organism ranges in size from  5 to 11 μm in length
                   Treatment and Prevention                         and 7 to 10 μm in width. T. tenax has five flagella from
                                                                    the anterior end, with four extending to the anterior por-
                   The medication of choice is metronidazole. Prevention is
                   accomplished by the avoidance of unprotected sex with   tion of the organism and one to the posterior. An undulat-
                                                                    ing membrane runs the length of the trophozoite as does
                   partners whose history is not known. Prompt treatment
                   and diagnosis of men who are asymptomatic and who   T. hominis. Stained specimens will yield a pear-shaped
                                                                    cell with an axostyle, a centrally located line extending vir-
                   may readily transmit the organism is important.
                                                                    tually throughout the length of the organism. One  nucleus
                                                                    is generally visible at the anterior end, and the size is the
                   NONPATHOGENIC FLAGELLATES                        general range for the smaller white blood cells, so it is easy
                   OF THE DIGESTIVE SYSTEM                          to miss T. tenax as easily as T. vaginalis, especially for an
                   (T. HOMINIS, T. TENAX)                           older specimen where the motility has decreased.
                   It is important to distinguish pathogenic from non-  Symptoms
                   pathogenic flagellates. Perhaps the most common of
                   these nonpathogenic organisms is that of Trichomonas   T. tenax may find crevices in the gingiva, the gum tissue
                   hominis. T. hominis is small and is usually not found or   that surrounds the neck of the teeth. Generalized inflam-
                   identified from stool specimens due to the concentration   mation may occur and is most prevalent in smokers and
                   of bacteria and undigested materials in the fecal speci-  those with poor dental hygiene. The condition is pre-
                   men. T.  hominis is found as a trophozoite and has no   dominantly asymptomatic, however.
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