Page 17 - Spring Newsletter2024
P. 17

Whole Genome Sequencing (WGS) to    We  have  recently  been  awarded  a
        sequence  a  PHPT  case  and  an    small   grant   from   CamVet   to
        epilepsy  case  (as  a  PHPT  control).  undertake  long-read  sequencing  of
        We  have  sequenced  a  further  case  the  candidate  region  in  an  attempt
        and  a  progressive  retinal  atrophy  to   identify   additional   variants.
        (PRA) case as a control, giving us two  Preliminary  data  suggests  that  the
        cases  and  two  controls.  These  data  region of interest is highly structurally
        have  enabled  us  to  independently  complex  and  very  difficult  to
        identify   the   chromosome   that  interrogate, but sequencing and data
        harbours  the  causative  genetic   analysis is ongoing.
        mutation for PHPT, however we have
        been unable to precise variant.


        Allergies                                        By Vikki Marshall
                                                         RVN APHC, CertCFVHNut

        It is coming up to that time of year  with your vet will allow your dog to
        where  we  can  start  to  see  the  get a correct diagnosis and treatment.
        beginnings of allergy flair ups in our
        4 legged companions.                 Allergic dermatitis
                                             Dogs suffering from skin allergies are
        In general there can be many causes  said to have allergic dermatitis which
        of allergies in dogs and some suffer  is the most common allergy in dogs.
        from  worse  symptoms  than  others.  Skin allergies are mainly caused by
        Allergies  in  dogs,  like  those  in  one, or a combination of, fleas, food
        humans, can have very varied causes  allergies and environmental (atopic)
        and  treatment  isn’t  always  as    factors.
        simple as we could wish for.  There
        are  several  types  of  allergies  your  Flea allergies - some dogs are allergic
        canine  companion  can  suffer  from  to flea saliva, and this can cause their
        including skin allergies, food allergies  skin  to  become  red  and  inflamed.
        and environmental allergies, making  This  allergy  is  generally  the  easiest
        matters  more  complicated,  the     to treat.
        symptoms of all of these can overlap  Another cause of skin allergies is food
        one another and often they can suffer  allergies or sensitivities.  Dogs that
        from two concurrent allergies.
                                             have  food  allergies  or  sensitivities
        Symptoms                             often  have  itchy  ears  or  paws  and
        The  symptoms  seen  in  dogs  may   often have gastrointestinal symptoms
        vary depending on the cause of the   such  as  chronic  diarrhoea  and  or
        allergy.    The  most  common  are  as  vomiting.  True food allergies are not
        follows: itchiness, hives, swelling of  that common; they are more likely to
        the face, ears, lips or ear flaps, red  suffer from a ‘sensitivity’.  Chicken is
        inflamed  skin,  diarrhoea,  vomiting,  a  common  protein  to  cause  food
        itchy ears or chronic ear infections,  sensitivities.
        itchy  runny  eyes,  sneezing  and   Environmental  allergens  can  also
        continual  licking.    An  appointment  affect the skin and can cause allergic
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