Page 337 - Pharmacology Mnemonics and Short Notes

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 Prophylaxis

 Treatment

 Treatment by this in immunocompromised persons

Adverse effects

Bloody Effects

 Thrombocytopenia

 Neutropenia

 Leukopenia

Also causes hepatic dysfunctions

Cidofovir

 Acyclovir and Ganciclovir  both are activated by viral enzyme
thymidine kinase

 Cidofovir  activated by host cell kinase and do not require viral

kinase

o Used where resistant to first two  to treat herpes

Uses

 Cidofovir  C  CMV viral infection treatment

Foscarnet

Phosphor formate derivative

 Does not require phosphorylation for activity

Used where resistance to other drugs has been developed

Mechanism

foscaRNAt  inhibit RNA polymerase & also inhibit DNA polymerase
(Like previous discussed drugs)
Contents

Pharmacology Mnemonics and Short Notes By Muhammad Ramzan Ul Rehman