Page 338 - Pharmacology Mnemonics and Short Notes

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Uses

 Herpes treatment

 Resistant Herpes in AIDS

 FosCARnet  Car  CMV virual infections

Anti-AIDS Drugs

No new Indian entered Pakistan

No • Non neucleoside reverse transcriptase inhibitors

new • Nucleoside reverse transcriptase inhibitor

Indian • Interase strand trasnferase inhibitors

entered • Entry inhibitors

Pakistan • Protease inhibitors

Nucleoside reverse transcriptase inhibitors (NRTIs)

Mechanism

Inhibit RNA dependant DNA polymerase (Reverse transcriptase)

Inhibit conversion of single stranded RNA into double stranded DNA

 Activate Host cell kinase  Triphosphates are formed  inhibit
reverse transcriptase enzyme
Contents

Pharmacology Mnemonics and Short Notes By Muhammad Ramzan Ul Rehman