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Hematuria                                                                                      Hemoptysis   1229



            Hematuria
  VetBooks.ir  Urinary Tract Origin (Kidneys, Ureters, Bladder, Urethra)  Hemophilia


               Trauma
                 Traumatic collection (e.g., catheter, cystocentesis)  Hepatic failure
                                                                     Thrombocytopenia
                 Renal biopsy                                      Renal infarction
                 Blunt trauma (e.g., hit by car)                   Renal granuloma
               Urolithiasis                                        Renal pelvic hematoma
               Neoplasia (any area of genitourinary tract)         Polycystic kidneys*
               Inflammatory disease                                Renal dysplasia*
               Urinary tract infection                             Vascular malformation
               Feline lower urinary tract signs/disease/interstitial cystitis  Renal telangiectasia (Welsh corgi)
               Chemically induced inflammation (e.g., cyclophosphamide-induced cystitis)  Idiopathic renal hematuria
               Glomerulonephritis*                              Genital Tract Contamination
               Parasites                                           Estrus
                 Dioctophyma renale                                Uterine subinvolution
                 Capillaria plica                                  Inflammatory, neoplastic, and traumatic lesions of the prostate, prepuce, or
               Bleeding disorder                                     vagina
                 Anticoagulant intoxication
                 Disseminated intravascular coagulation
           *Often only microscopic hematuria.
           Modified from Ettinger S, Feldman E: Textbook of veterinary internal medicine, ed 6, St. Louis, 2005, Saunders.

                                                                                                                      Differentials, Lists,   and Mnemonics


            Hemoptysis




            Differential Diagnosis Item  Key Feature(s)
            Airway foreign body         Often acute onset; history may be suggestive (e.g., hunting in tall grass), tracheobronchoscopy useful
            Bacterial pneumonia         Systemic signs common, underlying/predisposing cause (e.g., regurgitation, bronchiectasis) common
            Bronchiectasis              Uncommonly causes hemoptysis; history of chronic cough or respiratory disease
            Chronic bronchitis          Uncommonly causes hemoptysis unless coughing is extreme
            Coagulation factor deficiency  May be other sites of bleeding; confirm by coagulation profile (PT, aPTT)
            Congestive heart failure    Severe respiratory distress and expectoration of bloody fluid or foam from left-sided failure, heart murmur and harsh/loud lung
                                        sounds, crackles on auscultation
            Eosinophilic bronchopneumopathy  Uncommonly causes hemoptysis; peripheral eosinophilia possible
            Fungal pneumonia            Likelihood of diagnosis depends on geography, travel history, lifestyle, history of recent soil excavation, etc. Thoracic
                                        radiographs: multiple pulmonary patterns can occur, but multifocal nodular pattern can be confused with metastatic neoplasia.
            Heartworm infection         Uncommonly causes hemoptysis; consider geography, travel, and deworming history
            Iatrogenic                  Consistent patient history (e.g., intubation, lung aspirate, or biopsy)
            Lung lobe torsion           Emergent condition, often with pleural effusion; Afghan hound and pug overrepresented
            Neoplasia (primary)         Pulmonary or tracheal; nodule or mass identified on thoracic radiographs
            Neoplasia (metastatic)      Weight loss common, other tumor may be identified on exam (e.g., splenic hemangiosarcoma), thoracic radiographs highly
                                        suggestive
            Parasitic infection         Consider geography, travel, and deworming history
            Pulmonary hypertension      Uncommonly causes hemoptysis; echocardiographic identification of high-velocity tricuspid regurgitation
            Pulmonary thromboembolism   Uncommonly causes hemoptysis; diagnosis can be challenging; predisposing causes (e.g., heartworm disease, systemic
                                        hypercoagulable states) are important clues
            Thrombocytopenia/thrombocytopathy  Uncommonly causes hemoptysis; petechiae/ecchymosis often seen
            Trauma                      Patient history and lifestyle (e.g., off leash, roaming behavior), physical evidence of trauma
           Reproduced from the third edition in modified form.
           THIRD EDITION AUTHOR: Kelly Mitchell, DVM, DVSc, DACVIM






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