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Hepatopathy, Vacuolar 1231.e1

Hepatopathy, Vacuolar
VetBooks.ir Causes of Primary and Secondary Vacuolar

Hepatopathies in Dogs and Cats
Steroid Hepatopathy and Cloudy Change
• Steroid hepatopathy—secondary to high concentrations of circulating
corticosteroids (exogenous or endogenous)
• Vacuolar hepatopathy of Scottish terriers (overlap with steroid
hepatopathy?)
• Deficiency or toxicosis, e.g., severe cobalamin deficiency in dogs
• Secondary to hepatic insult from another disease process, e.g.,
congestive heart failure, neoplasia, other hepatobiliary disease,
gastrointestinal disease, renal disease, infectious disease
Steatosis
• Feline hepatic lipidosis—primary or secondary
• Toxicoses—for example, aflatoxin (dogs); vitamin A intoxication (cats)
• Secondary to canine familial hyperlipidemia
• Secondary to endocrine disease: hypothyroidism and diabetes mellitus
(dogs); occasionally hyperthyroidism (cats)
Modified from Watson PJ: Metabolic diseases of the liver. In Ettinger SJ, Feldman EC, Côté E: Textbook
of veterinary internal medicine, ed 8, St. Louis, 2017, Elsevier, p. 1659.

Differentials, Lists, and Mnemonics

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