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Tonsillar Disorders   1287


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  VetBooks.ir  Variables That May Affect Baseline Serum Thyroid Hormone Function Test Results in Dogs—cont’d
            Estrus (estrogen)
                                                           No effect on T 4
            Pregnancy (progesterone)
            Surgery/anesthesia                             Increased T 4
                                                           Decreased T 4
            Concurrent illness*                            Decreased T 4  and free T 4 ; depending on illness, TSH may increase, decrease, or not change
            Moderate/severe osteoarthritis                 No effect on T 4 , free T 4 , or TSH
            Drugs:
              Aspirin                                      Decreased T 4 , free T 4 ; no effect on TSH
              Carprofen                                    Decreased T 4 , free T 4 , and TSH
              Cephalexin                                   No effect on T 4 , free T 4 , or TSH
              Clomipramine                                 Decreased T 4 , free T 4 ; no effect on TSH
              Deracoxib                                    No effect on T 4 , free T 4 , or TSH
              Etodolac                                     No effect on T 4 , free T 4 , or TSH
              Glucocorticoids                              Decreased T 4  and free T 4 ; decreased or no effect on TSH
              Furosemide                                   Decreased T 4
              Ipodate                                      Increased T 4 , decreased T 3
              Methimazole                                  Decreased T 4  and free T 4 ; increased TSH
              Phenobarbital                                Decreased T 4  and free T 4 ; delayed increase in TSH
              Phenylbutazone                               Decreased T 4
              Potassium bromide                            No effect on T 4 , free T 4 , or TSH
              Progestogens                                 Decreased T 4
              Propylthiouracil                             Decreased T 4  and free T 4 ; increased TSH
              Sulfonamides                                 Decreased T 4  and free T 4 ; increased TSH
            Dietary iodine intake                          If excessive, decreased T 4 , and free T 4 ; increased TSH
            Dietary consumption of thyroid tissues         Increased T 4 , free T 4 , decreased TSH                   Differentials, Lists,   and Mnemonics
            Thyroid hormone autoantibodies                 Increased or decreased T 4 ; no effect on free T 4  or TSH
           *There is a direct correlation between the severity and systemic nature of illness and suppression of serum T 4  and free T 4  concentrations.
           T 3 , Triiodothyronine; T 4 , thyroxine; TSH, thyroid-stimulating hormone.
           Modified from Nelson RW, Couto GC: Small animal internal medicine, ed 4, St. Louis, 2009, Mosby.



            Tonsillar Disorders



            Differential Diagnosis Item  Key Feature(s)
            Primary viral tonsillitis  Bilaterally symmetrical enlargement; clinical signs of underlying disease present (e.g., ocular and nasal discharge and sneezing);
                                      fever common; virus isolation or PCR possible for confirmation but rarely necessary
            Primary bacterial tonsillitis  Bilaterally symmetrical enlargement; coughing present if Bordetella bronchiseptica; bacterial culture and sensitivity necessary to
                                      confirm
            Secondary tonsillitis     Bilaterally symmetrical enlargement; chronic vomiting, regurgitation, or coughing due to other concurrent disease; palate disorder
                                      (elongated or cleft); oropharyngeal contamination from periodontal disease, or licking at inflamed anal sacs or pyoderma
            Foreign body              Unilateral enlargement; grass awn, splinter, or porcupine quill visible on examination of tonsillar crypt
            Tonsillar cyst            Unilateral enlargement; fluctuant, fluid-filled mass; rare
            Squamous cell carcinoma   Unilateral irregular mass; biopsy required for confirmation
            Lymphoma                  Bilateral enlargement; often other lymphoid organs are affected (e.g., lymph nodes, spleen); fine-needle aspiration of tonsils for
                                      cytologic evaluation is possible under general anesthesia, but aspiration of other organs (e.g., lymph node) is often easier
           PCR, Polymerase chain reaction.
           Reproduced from the third edition in unabridged form.
           THIRD EDITION AUTHOR: Peter M. Foley, MSc, DVM, DACVIM













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