Page 263 - Small Animal Internal Medicine, 6th Edition

CHAPTER 12 Thromboembolic Disease 235

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Drugs Used in Cardiovascular Disorders

TRADE
GENERIC NAME NAME DOG CAT

Diuretics
Furosemide Lasix Chronic therapy: 1-3 (or more) mg/kg Chronic therapy: 1-2 (or more) mg/kg
Salix q8-24h PO (use lowest effective dose; q8-24h PO (use lowest effective dose;
maximum daily dose ~10[-12] mg/kg/ maximum daily dose ~8 mg/kg/day,
day, depending on renal function). depending on renal function).
Acute: 2(-4+) mg/kg initial bolus, then Acute: 1-2 mg/kg initial bolus, then
1-4 mg/kg q1-4h until RR decreases, 1-2 mg/kg q1-4h until RR decreases,
then 1-4 mg/kg q6-12h IV, IM, SC; or then 1-2 mg/kg q6-12h IV, IM, SC;
follow IV bolus with 0.6-1 mg/kg/h CRI or follow IV bolus with 0.3-0.6 mg/
until RR decreases (see Chapter 3) kg/h CRI until RR decreases (see
Chapter 3)
Torsemide Demadex 1 10 ( 12 - 8 ) of total daily furosemide dose, ~ 10 of total daily furosemide dose,
1
1
1
divide q12h (in place of furosemide) divide q12h (in place of furosemide)
Spironolactone Aldactone 2 mg/kg PO q24h (or divided q12h); can 1-2 mg/kg PO q24h (or divided q12h);
start lower can start lower
Chlorothiazide Diuril 10-40 mg/kg PO q12-48h (start qod with 10-40 mg/kg PO q12-48h (start qod
low dose) with low dose)
Hydrochlorothiazide Hydrodiuril 0.5-4 mg/kg PO q12-48h (start qod with 0.5-2 mg/kg PO q12-48h (start qod
low dose) with low dose)
Angiotensin-Converting Enzyme Inhibitors
Enalapril Enacard 0.5 mg/kg PO q12(-24)h 0.25-0.5 mg/kg PO q24h
Vasotec
Benazepril Lotensin 0.25-0.5 mg/kg PO q12(-24)h 0.25-0.5 mg/kg PO q24h
Captopril Capoten 0.5-2 mg/kg PO q8-12h 0.5-1.25 mg/kg PO q(8-)24h
Lisinopril Prinivil 0.25-0.5 mg/kg PO q(12-)24h 0.25-0.5 mg/kg PO q24h
Zestril
Ramipril Altace 0.125-0.25 mg/kg PO q24h 0.125 mg/kg PO q24h
Angiotensin-Receptor Blockers
Telmisartan Micardis 1 mg/kg PO q24h (1-)2 mg/kg PO q24h
Semintra
Irbesartan Avapro – 10 mg/kg PO q24h (experimental)
Continued