Page 266 - Small Animal Internal Medicine, 6th Edition

238 PART I Cardiovascular System Disorders

VetBooks.ir Drugs Used in Cardiovascular Disorders—cont’d

TRADE
GENERIC NAME NAME DOG CAT

Class IV
Diltiazem Cardizem Acute IV for rapid rate control of AF: Cat: Same?; Or 1.5-2.5 mg/kg (or
Cardizem-CD 0.05-0.10 mg/kg IV over 2-5 minutes, 7.5-10 mg/cat) PO q8h.
Dilacor XR can repeat if needed Sustained-release preparations:
Dilacor ER Acute IV for SVT: 0.1-(0.2) mg/kg over diltiazem ER, 30 mg/cat/day (one
2-5 minutes IV, can repeat to cumulative half of a 60-mg controlled-release
IV dose of 0.3-0.4 mg/kg; monitor tablet within the 240-mg gelatin
blood pressure. CRI (if frequent SVT capsule), can increase to 60 mg/day
recurrence): 0.002-0.006 mg/kg/min in some cats if necessary
(or 0.12-0.35 mg/kg/h) Cardizem-CD, 10 mg/kg/day (45 mg/
PO loading dose: 0.5 mg/kg PO followed cat ~ 105 mg of Cardizem-CD ≅
by 0.25 mg/kg PO q1h to a total of amount that fits into small end of No.
1.5(-2.0) mg/kg or conversion 4 gelatin capsule)
Oral maintenance (regular diltiazem):
initial dose 0.5-1 mg/kg (up to 2-3 mg/
kg) PO q8h
Extended release (diltiazem ER): 1-4 (up to
6) mg/kg PO q12h

Antiarrhythmic Drugs
Atropine 0.02-0.04 mg/kg IV, IM, SC. 0.04 mg/ Same
kg PO q6-8h.
Atropine challenge test: 0.04 mg/kg IV
(see Chapter 4, p. 97)
Glycopyrrolate Robinul 0.005-0.01 mg/kg IV, IM; Same
0.01-0.02 mg/kg SC
Propantheline Br Pro-Banthine 0.25-0.5 mg/kg or 3.73-7.5 (-15) mg/ —
dog PO q8-12h
Hyoscyamine Anaspaz, 0.003-0.006 mg/kg PO q8h —
Levsin
Sympathomimetics
Isoproterenol Isuprel 0.04-0.08 µg/kg/min CRI Same
Terbutaline Brethine 0.14 mg/kg, or 2.5-5 mg/dog, PO 0.1 -0.2 mg/kg, or 0.625-1.25 mg/
Bricanyl q8-12h cat, PO q12h
Theophylline ER Theolair 10 mg/kg PO q12h 10-15 mg/kg q24h
Drugs for Heartworm Disease
Heartworm adulticide
Melarsomine Immiticide See Chapter 10 —
Follow manufacturer’s injection instructions
carefully; 2.5 mg/kg deep IM for 1
dose, then 1 month later give 2.5 mg/
kg deep IM q24h for 2 doses
Heartworm prevention
Ivermectin Heartgard 0.006-0.012 mg/kg PO once a month 0.024 mg/kg PO once a month
Iverhart
Tri-Heart
Milbemycin oxime Interceptor 0.5-1.0 mg/kg PO once a month 2 mg/kg PO once a month
Sentinel
Trifexis