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CHAPTER 13   Clinical Manifestations of Nasal Disease   241



                                                                        BOX 13.1
  VetBooks.ir                                                    Differential Diagnoses for Nasal Discharge in Dogs
                                                                 and Cats

                                                                  Serous Discharge
                                                                  Normal
                                                                  Viral infection
                                                                  Early sign of etiology of mucopurulent discharge
                                                                  Mucopurulent Discharge with or without Hemorrhage
                                                                  Viral infection
                                                                    Feline herpesvirus (rhinotracheitis virus)
                                                                    Feline calicivirus
                                                                    Canine influenza virus
                                                                  Bacterial infection (usually secondary)
                                                                    Mycoplasma felis (possibly primary)
            FIG 13.1
            Typical grass awn. Seed heads from “foxtail” grasses have   Fungal infection
            stiff bristles that facilitate movement of the awns in one   Aspergillus
            direction and make it difficult for the awns to be expelled   Cryptococcus
            from the body. (Courtesy Lynelle R. Johnson.)           Penicillium
                                                                    Rhinosporidium
                                                                  Nasal parasites
            mucopurulent discharge is usually associated with neoplasia   Pneumonyssoides
            or mycotic infections.                                  Capillaria (Eucoleus)
              Persistent pure hemorrhage (epistaxis) can result from   Foreign body
            trauma, local aggressive disease processes (e.g., neoplasia,   Neoplasia
            mycotic infections), systemic bleeding disorders, or systemic   Carcinoma
                                                                    Sarcoma
            hypertension. Systemic hemostatic disorders that can cause   Malignant lymphoma
            epistaxis include thrombocytopenia, thrombocytopathies,   Nasopharyngeal polyp
            von Willebrand disease, rodenticide toxicity, and vasculiti-  Extension of oral disease
            des. Ehrlichiosis, Rocky Mountain spotted fever and, poten-  Tooth root abscess
            tially, bartonellosis can cause epistaxis through several of   Oronasal fistula
            these mechanisms. Nasal foreign bodies may cause hemor-  Deformed palate
            rhage after entry into the nasal cavity, but the bleeding tends   Allergic rhinitis
            to subside quickly. Bleeding can also occur after aggressive   Feline chronic rhinosinusitis
            sneezing from any cause.                              Canine chronic/lymphoplasmacytic rhinitis
            Diagnostic Approach                                   Pure Hemorrhagic Discharge (Epistaxis)
                                                                  Nasal disease
            A complete history and physical examination can be used to   Acute trauma
            prioritize the differential diagnoses for each type of nasal dis-  Acute foreign body
            charge (see Box 13.1). Acute and chronic diseases are defined   Neoplasia
            by obtaining historical information regarding the onset of   Fungal infection
            signs and by evaluating the overall condition of the animal.   Less commonly, other etiologies as listed for
            Acute processes, such as foreign bodies or acute feline viral   mucopurulent discharge
            infections, often result in a sudden onset of signs, including   Systemic disease
            sneezing, although the animal’s body condition is excellent.   Clotting disorders
            In  chronic processes,  such  as mycotic  infections  or neo-  •  Thrombocytopenia
            plasia, signs are present over a long period, and the overall   •  Thrombocytopathy
            body condition may be deleteriously affected. A history of   •  Coagulation defect
                                                                    Vasculitis
            gagging, retching, or reverse sneezing may indicate masses,   Hyperviscosity syndrome
            foreign bodies, or exudate in the caudal nasopharynx.   Polycythemia
              Nasal discharge is characterized as unilateral or bilateral   Systemic hypertension
            on the basis of both historical and physical examination
            findings. When nasal discharge is apparently unilateral, a
            cold microscope slide may be held close to the external nares
            to determine the patency of the side of the nasal cavity
            without discharge. Condensation will not be visible in front
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