Page 267 - Small Animal Internal Medicine, 6th Edition

CHAPTER 12 Thromboembolic Disease 239

VetBooks.ir Drugs Used in Cardiovascular Disorders—cont’d

TRADE
GENERIC NAME NAME DOG CAT

Selamectin Revolution 6-12 mg/kg topically once a month Same
Moxidectin/ Advantage 2.5 mg/kg moxidectin and 10 mg/kg 1 mg/kg moxidectin and 10 mg/kg
imidacloprid Multi imidacloprid topically once a month imidacloprid topically once a month

Antithrombotic Agents
Aspirin 0.5-1.0 mg/kg PO q24h (20-)81 mg/cat PO q72h
Clopidogrel Plavix 2-4 mg/kg PO q24h; (oral loading dose, 18.75 mg/cat (or 2-4 mg/kg) PO
10 mg/kg) q24h; oral loading dose, 75 mg/cat
Heparin Na 100-300 IU/kg IV, followed by 100 IU/kg IV, followed by 200 IU/kg
(unfractionated 100-300 IU/kg SC q8h (or CRI SC q8h (or CRI 600 IU/kg/day) for
heparin) 600-800 IU/kg/day) for 2-4 days or as 2-4 days or as needed
needed
Dalteparin Fragmin 50-100 U/kg SC q12-24h 100 U/kg SC q12-24h
Enoxaparin Lovenox 1.5 mg/kg SC q12-24h 1.5 mg/kg SC q12-24h
Warfarin Coumadin 0.1 mg/kg PO q24h initially; titrate based 0.25 mg/cat PO q24h initially; titrate
on PT/INR (see p. 233) based on PT/INR (see p. 233)
Fondaparinux Arixtra — 0.06 mg/kg SC q12h for
thromboprophylaxis
0.2 mg/kg SC q12h for thrombosis
treatment
Rivaroxaban Xarelto 0.5-1.0 mg/kg PO q24h 2.5 mg/cat PO q24h
Apixaban Eliquis — 0.625 mg/cat PO q12h
CHF, Congestive heart failure; CRI, constant-rate infusion; IM, intramuscular; INR, international normalization ratio; IV, intravenous; PO, by
mouth; PT, prothrombin time; RR, respiratory rate; SC, subcutaneous.