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Dental Management of Patients with Hypertension and

             Cardiac Complications from Hypertensive Heart Diseases

                           Authors: Juhee Kim, Angela DeBartolo, DDS, and Analia Veitz-Keenan, DDS


        Introduction                                            Complications of hypertensive heart diseases frequently seen
        Hypertension is a major risk factor of cardiovascular disease and   in dental clinic
        is currently ranked as the leading contributor to global disabili-
                          1
        ty-adjusted life-years.  According to the recent National Center for   Atrial fibrillation
        Health Statistics (NCHS) data brief, the prevalence of hyperten-
        sion in adults aged 18 and over in the United States was 45.4%,   Being the most frequently encountered arrhythmia, atrial fibrilla-
        and increased with age. The prevalence of hypertension was lower   tion (AF) is a multifactorial disease in which the heart beats irreg-
        in 18 to 29-year-old adults at 22.4%, which increased to 54.5%   ularly due to abnormal conduction. The irregular heartbeat starts
        in 40-59 years of age and to 74.5% in adults at 60 years old or   from the upper chambers of the heart and, if such a condition is
        older.  Along with its high prevalence, hypertension is also a ma-  left untreated, will lead to heart failure, decreased quality of life,
             2
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        jor source of financial burden both worldwide and in the United   and even death.  Along with its high morbidity and mortality rate,
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        States. It accounts for about 10% of global healthcare expenditures   the recurrence rate of AF is also high being about 40 to 50%.
        and about 15.1% of total hospital costs in the United States. 3,4  The symptoms of AF include but not limited to palpitations, short-
                                                                ness of breath, chest pain, fatigue, and malaise. However, since
        In addition to its high prevalence and financial burden, hyperten-  AF is often asymptomatic, it is imperative that clinicians review
        sion often leads to serious consequences and causes cardiac com-  patient’s medical history and underlying conditions, particularly
        plications such as atrial fibrillation, coronary artery disease, valvu-  hypertension, thoroughly.  Treatment of AF often involves heart
                                                                                    11
        lar disease, ischemic heart disease, arrhythmia, and others.  Thus,   rate and rhythm control through regimens such as antiarrhythmic
                                                       5
        it is imperative to understand the current burden of hypertension   medications and electrical devices (i.e pacemaker), and anticoag-
        and hypertension-related cardiac and other systemic complications   ulation medications.
        to manage hypertensive patients with appropriate strategies.
                                                                Coronary artery disease
        Despite its high prevalence, about 37.3% of patients in the United
        States still have undiagnosed hypertension.  As dental practitioners   Coronary artery  disease  (CAD) is the  most common  cause  of
                                          6
        often see patients on a regular basis, it would be beneficial if they   death worldwide  and is the most common type of heart disease
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        would operate as the frontline to monitor patients’ blood pressure   in the United States. CAD occurs when the coronary artery gets
        (Table 1), assess their need for medical consultation, and ultimate-  narrowed or blocked by buildup of plaque, which is made of cho-
        ly help prevent potential systemic complications of hypertension.   lesterol deposits in the walls of the coronary arteries.  The partial
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        Furthermore, it is incumbent on all oral healthcare providers to be   obstruction of the coronary arteries will reduce the blood supply
        aware of appropriate management strategies. In managing patients
        with hypertension and hypertension-related cardiac complications,   to the heart and ultimately lead to ischemic heart disease, which
        understanding the potential side effects and interactions of antihy-  would be further discussed in the next section. Although the symp-
        pertensive, anticoagulant, and antiplatelet agents, and the potential   toms of CAD involve chest pain, fatigue, malaise, dizziness, and
        risk of using local anesthesia with epinephrine are all  of grave   nausea, it is usually asymptomatic and unnoticed by patients un-
        importance. Thus, dental practitioners can aid in not only prevent-  til they have a heart attack. Thus, it is critical to review patients’
        ing systemic complications of hypertension, but also provide the   risk factors for CAD regularly such as hypertension. Treatment of
        most appropriate treatment to patients with hypertension and hy-  CAD often includes anti-cholesterol, antihypertensive, anticoagu-
        pertension-related cardiac complications, and ultimately promote   lant, and antiplatelet medications.
        patient-centered care.
                                                                Procedural  treatment  methods include  balloon  angioplasty  and
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        Therefore, the purpose of this paper is to: 1) provide a review of   stenting, and coronary bypass graft (CABG) surgery.
        the four complications from hypertensive heart disease frequently
        seen in dental clinics - atrial fibrillation, coronary artery disease,   Ischemic heart disease
        ischemic heart disease, and valvular disease, 2) inform the reader
        of the appropriate dental management of patients with hyperten-  As aforementioned, CAD leads to ischemic heart disease and the two
        sion and such complications, and 3) ultimately ensure that patients   terms are interchangeable. Ischemic heart disease is a condition in
        with such conditions receive proper attention and management.  which blood and oxygen supply is limited or blocked due to plaque
                                                                buildup or narrowing of blood vessels. If the blood and oxygen sup-
            Blood Pressure     Systolic            Diastolic    ply to the heart is completely blocked, necrosis of heart muscle cells
                                                                takes place and leads to myocardial infarction, which is also known
              Category         pressure             pressure    as a heart attack.  The treatment regimens and procedural methods
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                               (mmHg)               (mmHg)
               Normal             120       and        80       for ischemic heart disease are similar to those of CAD.
               Elevated        120-129      and        80       Valvular heart disease
               Stage 1         130-139      or       80-89      Valvular heart disease is a condition in which a valve in the heart
             Hypertension                                       does not function properly due to either  congenital  or acquired
                                                                cause. With malfunctioning heart valves, the heart is not able to
               Stage 2            140       or         90       regulate the blood flow properly. Valvular heart disease is often
             Hypertension                                       asymptomatic  until  it progresses to an advanced  stage, and its
        Table 1. Updated Blood Pressure Categories by the American College of   symptoms usually include shortness of breath, chest pain, fatigue,
        Cardiology/American Heart Association (ACC/AHA) in 2017. 7,8  malaise, fever, arrhythmia, and dizziness. According to the CDC,
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