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The Oral Healthcare Providers’ Responsibility in

                                  Treating the Patient with Diabetes


                             Authors: Debra M. Ferraiolo, DMD, FAGD and Analia Veitz-Keenan, DDS

        Introduction                            Type 2                             Blood sugar levels using a glucometer can
        Diabetes has reached epidemic proportions                                  also be used by the patient to monitor con-
        in the United States. In 2020, 37.3 million   •  90 - 95% of all diagnosed diabetics  trol  on a  day-to-day basis.  A dentist  can
        people were afflicted. Of these, 8.5 million   •  Occurs due to insulin resistance or   maintain a glucometer in the office to check
        were undiagnosed and discovered on rou-     relative insulin deficiency    levels on the day of a surgical procedure, for
        tine exams or when symptoms developed.    •  Usually diagnosed in adults but an   hypo/hyperglycemic events or screening if
        In the US, 38% of the population have been   increased number of children, teens   you have concerns your patient may be an
        diagnosed  with prediabetes.  Additionally,   and young adults are being diag-  undiagnosed diabetic.
        1.4 million Americans receive a diabetes di-  nosed
        agnosis every year and it is the 7  leading   •  Managed with lifestyle
                                    th
        cause of death in the United States. 1      changes and/or medi-
                                                    cations  that  stimulate
        Why is it important for the oral healthcare   insulin release or insu-
        provider to be familiar with diabetes and   lin sensitizers (may in-
        its management in the dental setting? Oral   clude insulin)
        healthcare providers will encounter patients
        with diabetes frequently in their practice.   Gestational
        Therefore, it is important to have an under-  •  Occurs in the second
        standing of the disease itself, as well as the
        signs and symptoms in the undiagnosed pa-   half of pregnancy in
                                                    women who have never
        tient, including the oral manifestations of di-
                                                    had diabetes
        abetes. Dentists should also be well versed in   •  Caused  by placental
        assessing the patient’s glycemic control and   hormones causing insu-
        how to manage the poorly controlled patient
        and, if and when modifications are needed,   lin  resistance  and  rela-
                                                    tive insulin deficiency
        and what those modifications should be. Di-
        abetes impacts oral health and vice versa. 2.   •  Child is at increased
                                                    risk of obesity and dia-
        Background 3                                betes later in life
        Diabetes  is a  chronic  metabolic  disease   •  Resolves after  baby is
                                                    born, but increases the
        that leads to hyperglycemia  as a result of                      Figure 1. American Diabetes Association - Diabetes control. 4
        the body’s inability  to produce or process   mother’s risk of diabe-
                                                    tes later in life
        insulin properly. Insulin, produced by pan-
        creatic  beta cells, is used for processing                                Oral Manifestations
        carbohydrates, proteins and lipids as well as   Other types                Oral  manifestations  of  uncontrolled/undi-
        glucose storage in the liver. Hyperglycemia   •  Drug/chemical induced (steroids)  agnosed diabetes can include xerostomia,
        develops when the beta cells lack the abili-  •  Exocrine pancreatic disease  burning sensation, impaired wound healing,
        ty to produce insulin or if the cells become   •  Infections               increased risk of post-op and candida infec-
        insensitive to insulin. Key symptoms in the                                tions, and enlargement of the parotid gland.
        non-diagnosed or poorly controlled diabetic   The term prediabetes is used when glucose   Much has been reported in regard to the con-
        are thirst, hunger and/or frequent urination.   levels  are elevated but not to the point of   nection between diabetes and gingivitis and/
        Hyperglycemia  can  cause  dysfunction  of   diabetes. This patient is at high risk of de-  or periodontitis. Diabetes results in an en-
        the immune system and, as a result, undi-  veloping diabetes, as well as heart disease   hanced inflammatory response and narrow-
        agnosed or poorly controlled diabetics are   and stroke. Patients with this diagnosis will   ing of the microvasculature, which puts the
        at increased risk of infection. Long-term ef-  be recommended for lifestyle changes and/  patient at higher risk for periodontitis. As a
        fects of poorly controlled diabetes include   or prescribed Metformin  with the goal of   result, it should be no surprise that a patient
        cardiovascular events, retinopathy, chronic   delaying the progression or preventing the   with uncontrolled diabetes would present
        kidney  disease  (CKD),  amputation  of  ex-  diagnosis of diabetes.       with  a  greater  manifestation  of  periodon-
        tremities, and diabetic neuropathy.                                        tal disease.  Also, the hyperglycemic state
                                             How is Glycemic Control Assessed?     impacts  chemotaxis of  WBCs and  causes
        Diabetes Classification              The hemoglobin A1C blood test measures   increased risk of infections, which is listed
                                                                                   as a comorbidity along with other health is-
           Type 1                            the amount of glycosylated hemoglobin in   sues that develop over time or progress more
                                             the patient’s RBCs. Since it assesses the av-
                                                                                                             5
             •  5 – 10 % of all diabetics    erage blood sugar levels over the past three   rapidly in patients with diabetes. There has
                                                                                   been mention of a bidirectional association
             •  Believed to be autoimmune    months, it is considered the “gold standard”   between periodontal disease.  Some diabetic
                                             in assessing glycemic control. A result > 6.5
             •  No insulin production due to loss of                               patients with a good response to non-surgi-
               pancreatic tissue             indicates diabetes. Patients with diabetes are   cal periodontal treatment also had an A1C
                                             considered well controlled with an A1C <7.
             •  Usually diagnosed in children, teens   Those patients with an A1C >9 are consid-  indicating better diabetic control.   This has
                                                                                                              6,7
               and young adults                                                    led to some discussion that in patients with
             •  Managed with insulin         ered poorly controlled and will require den-  diabetes, treatment of periodontal disease
                                             tal  modifications,  depending  on  the  treat-
             •  No prevention                                                      may slightly improve glycemic control.
             •  Genetic predisposition       ment being performed.
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