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Etiologic Patterns of Ischemic Stroke in Young Adults in Prasat

Neurological Institute, from 2008 to 2013

Piyasak Naumna MD., TasaneeTantirittisak M.D.

Prasat Neurological Institute, Department of Medicalo Services,

Ministry of Public Health, Bangkok, Thailand

Objectives: To evaluate the etiologic patterns of young onset ischemic stroke

in Prasat Neurlogical Institute (PNI) and correlate between risk factors and

outcomes.

Materials and Methods: Retrospective study of young onset ischemic stroke

patients (aged 15-45 years) between 2008 and 2013 was performed. Five

hundred and forty nine patients including in-patient and out-patient of PNI

were included in the study. Demographic data, risk factors, date of onset and

clinical outcomes were evaluated by reviewed medical records.

Results: Prevalence of young onset ischemic stroke in PNI was 2.4%. The

majority of the ischemic stroke patients were arterial strokes; n=543 (98.9%)

while 6 patients (1.1%) were venous stroke. With Trial of Org 10172 Acute

Stroke Treatment (TOAST) classification, the predominant stroke subtype was

small vessel occlusion-SVO (42.1%) followed by undetermined of etiology-UD

(27.0%), large artery atherosclerosis-LAA (17.8%), stroke of other determine

etiology-OD (6.9%) and cardioembolism-CE (6.2%). In the OD category, we

found the recognized causes of ischemic strokes which include vascular

dissection [n= 17; (3.1%)], Moyamoya disease [n=7; (1.3%)], venous sinus

thrombosis [n=6; (1.1%)], anti-phospholipid syndrome [n=3; (0.5%)], protein C

th
19 Annual Academic Meeting of Prasat Neurological Institute, 2015