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group, but not in RRMS group. The RNFLT, macular volume and macular

thickness in optic neuritis eye (ON-eye) were not significantly different between

NMO, NMOSD and RRMS. Regarding of AQP4-IgG serostatus, there is no

difference in RNFLT between two groups in terms of ON-eye and nonON-eye.

In nonON-eye, the RNFLT was not different between NMO, RRMS, and control

group.

Conclusion: The RNFLT average of NMO group was lower significantly when

compare to NMOSD, RRMS and normal healthy control group. This suggests the

more axonal damage in NMO patients. AQP4-IgG serostatus has no effect on

severity of axonal damage in NMO. This study data could not demonstrate the

utility of OCT to differentiate between NMOSD from MS.

2015 Annual Academic Research Study Presentations