Page 61 - Children Bookt.pdf

Table 16 : Recommendations for co-management of TB and HIV in infants and
children diagnosed with TB while on ART
Time of TB Underlying cause Considerations for ART regimen
diagnosis in of TB ART following
relation to initiation of TB
ART treatment
(rifampicin-
containing regimen) a

TB attributable to Continue ART Continue on standard
primary infection but assess for two NRTIs
(consider at any need to change §++!6
¥
b
time during ART, ART regimen if on NVP , substitute
depending on ‚

} with EFV if the child
c

&
}` therapy should ˆx
¥
be used to if <3 years increase
Child on
evaluate need +/ &
6
for change or Substitute NNRTI
regimen with

+!6
2 NRTIs
regimen
+ NNRTI
TB as part of IRIS
diagnosed with
@
_
TB
months of ART)
TB as a sign of Consider consultation
treatment failure of
&
6

construction of
(consider only second-line regimen d
after at least 24
weeks of ART)
TB attributable to Assess for need to Continue same
primary infection

‚ regimen,consider
Child on
(consider at any response to TB adding RTV to achieve
standard
time during ART, therapy full therapeutic dose
PI regimen
depending on should be used to (increase RTV until
(2 NRTIs

&
}` evaluate need for same dose as LPV in
+ boosted PI)
changing or stopping
*`
diagnosed
Consider consultation
with TB

&
construction of salvage
regimen d
TB as a sign of Consider consultation
treatment failure of
&
second-line construction of salvage
regimen regimen d

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