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A28    SCIENCE
              Thursday 27 sepTember 2018
            Antibiotics for appendicitis? Surgery often not needed




            By LINDSEY TANNER                                                                      offering  antibiotics  instead  ish  study  all  had  conven-
            CHICAGO  (AP)  —  When                                                                 of  surgery  and  Salminen  tional  incisions  rather  than
            emergency  tests  showed                                                               says she occasionally does  the  less  invasive  "keyhole"
            the telltale right-sided pain                                                          too.  The  journal  editorial  surgeries  that  are  more
            in Heather VanDusen's ab-                                                              says  appropriate  patients  common  for  appendix  re-
            domen  was  appendicitis,                                                              should  be  given  that  op-  moval in the United States.
            she figured she'd be quick-                                                            tion.                        The  non-surgery  patients
            ly wheeled into surgery. But                                                           The  study  involved  about  received  three  days  of  IV
            doctors offered her the op-                                                            500 Finnish adults who had  antibiotics  in  the  hospital,
            tion of antibiotics instead.                                                           CT scans to rule out severe  followed by seven days of
            A  new  study  from  Fin-                                                              cases.                       pills at home.
            land  shows  her  choice  is                                                           Half were treated with an-   Dr. Giana Davidson, a Uni-
            a  reasonable  alternative                                                             tibiotics; the others had sur-  versity  of  Washington  sur-
            for  most  patients  with  ap-                                                         gery.                        geon, is involved in a simi-
            pendicitis.  Five  years  after                                                        Among  the  antibiotics  pa-  larly  designed  multicenter
            treatment  with  antibiotics,                                                          tients,  100  ended  up  hav-  U.S. study that may answer
            almost  two-thirds  of  pa-                                                            ing surgery within five years  whether  similar  benefits
            tients  hadn't  had  another                                                           of  treatment  —  most  for  would be seen for antibiot-
            attack.                                                                                a  suspected  recurrence  ics versus "keyhole" surgery.
            It's  a  substantial  change                                                           of  appendicitis  in  the  first  Davidson  called  the  Finn-
            in  thinking  about  how  to                                                           year.  Seven  of  them  did  ish study "a critical piece to
            treat  an  inflamed  appen-                                                            not have appendicitis and  the puzzle but I don't think
            dix.  For  decades,  appen-                                                            likely  could  have  avoided  it  answers  all  of  the  ques-
            dicitis has been considered                                                            surgery. The results suggest  tions."
            a  medical  emergency  re-   In this 2016 photo provided by the University of Washington, Dr.   the success rate for antibi-  Heather  VanDusen  was
            quiring  immediate  surgery   Linda  Vorvick  examines  Heather  VanDusen  at  UW  Neighbor-  otic  treatment  was  almost  treated at the University of
            to  remove  the  appendix    hood Clinic in Seattle.                                   64  percent,  the  authors  Washington  in  2016.  She
            because  of  fears  it  could                                         Associated Press  said.                       said  she  chose  antibiotic
            burst,  which  can  be  life-                                                          About 1 in 4 surgery patients  treatment  partly  to  avoid
            threatening.                 lead author and a surgeon  Journal  of  the  American  had complications, includ-      surgery scars, and now of-
            But  advances  in  imaging  at  Turku  University  Hospital  Medical Association.      ing  infections  around  the  fers  advice  to  patients  for
            tests, mainly CT scans, have  in Finland.                 A  journal  editorial  says  "it's  incision,  abdominal  pain  Davidson's study.
            made it easier to determine  Her  study  in  adults  is  the  a  new  era  of  appendicitis  and  hernias,  compared  "I knew the worst case sce-
            if an appendix might burst,  longest  follow-up  to  date  treatment."                 with  only  7  percent  of  an-  nario was ending up back
            or if patients could be safe-  of  patients  treated  with  Appendix  removal  is  the  tibiotics patients. Antibiotic  in  the  hospital  so  why  not
            ly treated without surgery.  drugs instead of surgery for  most common emergency  patients  had  11  fewer  sick  try  antibiotics  first,"  said
            The  results  suggest  that  appendicitis and the results  surgery  worldwide,  with  days on average than the  VanDusen,  who  works  in
            nearly two-thirds of appen-  confirm  one-year  findings  about  300,000  performed  surgery  group.  In  the  first  university communications.
            dicitis  patients  don't  face  reported three years ago.  each  year  in  the  United  year,  their  treatment  costs  She said she has done well
            that risk and may be good  Research  has  also  shown  States  alone,  said  Salmin-   were  about  60  percent  since  her  treatment,  but
            candidates  for  antibiotics  antibiotics  may  work  for  en.  She said the results from  lower.  A  cost  analysis  for  that the biggest drawback
            instead.                     some children with appen-    her study suggest many of  the full five years wasn't in-  "is  wondering,  with  every
            "It's a feasible, viable and a  dicitis.                  those  surgeries  could  be  cluded in the published re-  episode  of  stomach  or
            safe  option,"  said  Dr.  Pau-  The  Finnish  results  were  avoided.                 sults.                       bad gas, if it could happen
            lina  Salminen,  the  study's  published  Tuesday  in  the  U.S.  doctors  have  started  Surgery patients in the Finn-  again."q

            Big changes about small fish are in store for fishermen




            By PATRICK WHITTLE           Atlantic  herring  is  a  small,  Oceanic and Atmospheric  mid-sized trawlers from sen-  Debate over the proposed
             Associated Press            schooling  fish  that  is  the  Administration  has  said  a  sitive  spawning,  feeding  changes  has  prompted  a
            Fisheries   managers    are  target  of  an  industry  that  recent  assessment  of  the  and  nursery  habitat.  The  clash between herring fish-
            adopting  a  host  of  poten-  collects  more  than  100  herring  stock  shows  a  de-  buffer extends 12 miles (19  ermen,  harvesters  of  other
            tially major changes for At-  million  pounds  (45  million  cline.                    kilometers)  from  the  coast  species,   conservationists
            lantic herring, an economi-  kilograms)  of  catch  every  On Tuesday, the New Eng-    in  most  areas  but  will  ex-  and  stakeholders.  The  her-
            cally  important  fish  that  year. The fish is also the sub-  land  Fishery  Management  tend to nearly 20 miles (32  ring  fishery  wants  to  make
            serves as a key part of the  ject  of  concern  from  envi-  Council  adopted  a  new  kilometers)  around  Cape  sure  it  isn't  unfairly  penal-
            ocean  ecosystem  in  New  ronmentalists  and  fishery  formula that will help guide  Cod in Massachusetts.         ized  for  the  decline  of  the
            England.                     managers, as the National  how  it  sets  catch  limits  in  Peter  Baker,  director  of  species,  said  Jeff  Kaelin,
                                                                      the  future.  Catch  limits  U.S.  Ocean  Conservation-   who  works  in  government
                                                                      will  change  based  on  the  Northeast  for  the  Pew  relations for herring harvest-
                                                                      health of the fishery, which  Charitable  Trusts,  praised  er Lund's Fisheries of Cape
                                                                      is  updated  through  stock  the council's actions.       May, New Jersey.
                                                                      assessments.                 "Protecting  these  sensitive  "Environment  plays  a  big-
                                                                      The council aims to further  areas  from  intensive  fish-  ger  part  than  the  level  of
                                                                      reduce catch limits to pre-  ing and rebuilding the her-  fishing  pressure  that  has
                                                                      vent  overfishing  of  herring.  ring population will directly  been allowed," Kaelin said.
                                                                      But  there  were  no  projec-  benefit marine wildlife and  Herring are important eco-
                                                                      tions available Tuesday.     the coastal businesses that  nomically  because  they
                                                                      It also approved a coastal  depend  on  them,"  Baker  serve as key bait for the lob-
                                                                      buffer  zone  to  keep  out  said in a statement.         ster and tuna industries.q
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