Page 446 - Essential Haematology

432 / Index

amyloid P 282, 284, 285 anagrelide 210 antithrombin
amyloidosis 282, 283, 284 anaplastic large cell lymphoma 258, defi ciency 366–7, 418
classifi cation 283 259, 270 neonates 418
anaemia 25–9, 30–1, 32 anaplastic lymphoma kinase 270 antithymocyte globulin 293
age 25 androgens, aplastic anaemia 293 aplastic anaemia 289–94
ALL 224 angiodysplasia 45 causes 289
bacterial infections 388 anisocytosis 29 clinical features 292
blood fi lm 28 ankyrin 22, 24 congenital 289–90
bone marrow examination 28–9 anti-β 2 -GPI antibodies, diagnosis 292–3
classifi cation 26–9 thrombophilia screening Fanconi-type 289, 290
clinical features 25–6 370 idiopathic acquired 292
CLL 236, 237 anti-D antibody 399, 402, 419 laboratory fi ndings 292
congestive heart failure 387 sensitization 419, 420 pathogenesis 289
erythropoiesis antibiotics secondary 292
assessment 29, 32 cytotoxic in haematological treatment 293–4, 302
ineff ective 29 malignancies 174, 176 viral hepatitis 387–8
erythropoietin levels 19 haematological malignancies apoptosis 11–13
haemolytic disease of the 169, 170 argatroban 376
newborn 422 anticardiolipin antibodies 370 arsine poisoning, haemolytic
HIV infection 391 anticoagulant drugs, venous anaemia 86
hypochromic 34–49 thrombosis 371–6, 377 arterial thrombosis 363–4
hypothyroidism 388 anticoagulant pathways, antithrombin defi ciency 367
laboratory fi ndings 26–9 infl ammation 369 risk factors 363–4
malignancy 382, 384 antiemetic therapy with Aspergillus, allogeneic stem cell
multiple myeloma 277, 281 chemotherapy 168 transplantation 308
myelodysplasia 217 antifolate drugs 71 Aspergillus fumigatus, haematological
neonates 416, 417, 418 antifungal drugs 171 malignancies 171, 172
non-Hodgkin lymphoma 257 antigen presentation, macrophages aspirin
physiological of pregnancy 414 114 defective platelet function 341
red cells antigen presenting cells (APCs) polycythaemia vera 207
inclusions 30 133, 135 venous thrombosis 378, 379
shape/size variation 29 antigen–receptor gene arrangements atherosclerosis 363
renal failure 385–7 131–2, 133 ATRA syndrome 183
severity 25 antiglobulin test 404–5 ATRA therapy for AML 183, 186
signs 25–6 see also direct antiglobulin test atrophic gastritis 41
speed of onset 25 (DAT) parenteral iron 45
symptoms 25 antihuman globulin (AHG) 404, 405 vitamin B 12 defi ciency 64
thalassaemia major 95 antilymphocyte globulin, aplastic autoimmune haemolytic anaemia
viral infections 390 anaemia 293 (AIHA) 82–4, 138
see also iron defi ciency anaemia; antimetabolites, haematological CLL 237
named conditions malignancies 173, 174, Mycoplasma pneumoniae 389
anaemia of chronic disorders 46–7, 176 systemic lupus erythematosus
382 antiphospholipid syndrome 369–70 385
bacterial infections 390 antiplatelet drugs autoimmune thrombocytopenic
malaria 391 defective platelet function 341–2 purpura 138, 334–7
rheumatoid arthritis 385 disseminated intravascular clinical features 335
systemic lupus erythematosus 385 coagulation 358 diagnosis 336, 337, 342–3
anaemia of prematurity 418 venous thrombosis 378–9 pathogenesis 335