Page 450 - Essential Haematology

436 / Index

coumarins 374–6 deferasirox 56 pathogenesis 356, 357
Creutzfeldt–Jakob disease, new deferiprone 56 pregnancy 416
variant (nvCJD) 403, deferoxamine 54–6 protein C defi ciency 367
404 demethylating agents, thrombocytopenia 338
transmission prevention 409 haematological thrombosis treatment 358
Crohn’s disease, parenteral iron 45 malignancies 175, 176 treatment 358
cross-matching of blood 405, 406 dendritic cell(s) 121–2, 133, 135 divalent metal transporter 1 (DMT-
cryoprecipitate 411 disorders 122 1) 35–6, 38, 39
haematological malignancies 168 spleen 144 gene mutations 46
preparation 398 dendritic cell neoplasms 270 DNA methyl-transferase inhibitors
cryosupernatant 398 WHO classifi cation 429 219
cyclin-dependent protein kinases desmopressin 319 DNA methylation 158
(Cdk) 11 haemophilia A 349–50 DNA microarray platforms 160–1,
cyclin proteins 11 von Willebrand disease 353 162
cystitis, haemorrhagic 310 1-diamino-8-D-arginine vasopressin DNA synthesis defects 71
cytochrome c 11, 12 (DDAVP) see desmopressin Donath–Lansteiner antibody 84
cytokinesis 10 diet donor leucocyte infusions (DLI)
cytomegalovirus (CMV) 404 iron defi ciency 41, 42 allogeneic stem cell
allogeneic stem cell iron fortifi cation 45 transplantation 310, 311,
transplantation 308, 309 diff erentiation syndrome 183 312

interstitial pneumonitis diffuse large B-cell lymphomas chronic myelogenous leukemia
309–10 (DLBCL) 267–8 310, 311
blood products 167–8, 409 HIV infection 267, 268, 391 non-Hodgkin lymphoma 311
blood transfusion 404, 409 dihydrofolate (DHF) 62–3 DRB genes 305
glandular fever 135 2,3-diphosphoglycerate (2,3-DPG) drug-induced haemolytic anaemia
haematological malignancies 21, 22, 23 86
170, 171 dipyridamole, venous thrombosis immune 84–5
interstitial pneumonitis 309–10 378, 379 drug-induced immune
lymphocytosis 390 direct antiglobulin test (DAT) 82, thrombocytopenia 334,
cytotoxic drugs 404–5 337, 338

antibiotics for haematological cold autoimmune haemolytic Duffy antigen chemokine receptor
malignancies 174, 176 anaemias 84 (DARC) gene 119
haematological malignancies warm autoimmune haemolytic dysfi brinogenaemia 388
172–3, 174–5, 176 anaemia 83 dyskeratosis congenita 291
direct thrombin inhibitors 376 dysphagia, iron defi ciency 39, 41
D disseminated intravascular
D-cyclin genes 278 coagulation (DIC) 85, E
dabigatran 376 327, 355–8 E2F transcription factor 9
dactylitis 100, 102 AML 181 eculizumab 87
danazol 211 bacterial infections 388–9 Ehlers–Danlos syndrome 331
dasatinib 198, 199 causes 356 elliptocytosis 24
deep vein thrombosis clinical features 356–7 eltrombopag 343
diagnosis 370–1 giant cavernous haemangioma chronic idiopathic
diagnostic imaging 365 331 thrombocytopenic
mechanical methods of laboratory fi ndings 357, 358 purpura 336, 337
prophylaxis 377 liver disease 355 Embden–Meyerhof pathway 22, 23
postoperative 368 mucin-secreting adenocarcinoma defects 81–2
recurrent 364, 365 368, 383 emboli 363