Page 176 - Physiology and Pathophysiology MNU 2024-2025 نظرى

Clinical pharmacy 2024/2025 Level 2 Pharm D Physiology and Pathophysiology (MD303)

Integrative cardiovascular responses

A) Changes in gravitational forces (Standing)
1- When a person stands blood pools in veins of lower limbs

2- This ↑ local venous pressure and↑ fluid filtration into the

interstitium
 If the lymphatics are unable to return it to the circulation ➔
edema لشف ولف ةيومدلا ةرودلل ايلاخلا نم مدلا ةداعا نع لوؤسم ي و افميللا زاهجلا
3- Venous return↓ ➔↓ stroke volume cardiac output➔ ↓ Pa
 If cerebral blood pressure becomes very low ➔ Fainting may
occur

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